Using a dietary supplement to prevent HPV infection persistence

A Pilot Study to Test the Effect of the Association of Epigallocatechin Gallate (EGCG), Folic Acid and Vitamin B12 in Preventing the Persistence of Human Papilloma Virus (HPV) Infection.

NA · Lo.Li.Pharma s.r.l · NCT06285357

This study tests if a dietary supplement with EGCG, folic acid, and vitamin B12 can help people with cervical HPV infections avoid long-term problems that could lead to cancer.

Quick facts

PhaseNA
Study typeInterventional
Enrollment100 (estimated)
Ages25 Years to 65 Years
SexFemale
SponsorLo.Li.Pharma s.r.l (industry)
Locations1 site (Modena, Modena)
Trial IDNCT06285357 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of a dietary supplement containing epigallocatechin gallate (EGCG), folic acid, and vitamin B12 on patients with cervical HPV infections. The goal is to determine whether this combination can help prevent the persistence of HPV, which is known to lead to cervical cancer. Participants will be monitored for changes in HPV status following the intervention. The study aims to provide insights into alternative treatment options for HPV infections.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals who have tested positive for high-risk HPV DNA.

Not a fit: Patients who do not have high-grade squamous intraepithelial lesions (HSIL) may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could offer a new preventive strategy against the persistence of HPV infections, potentially reducing the risk of cervical cancer.

How similar studies have performed: While there is ongoing research into dietary supplements for HPV treatment, this specific combination of EGCG, folic acid, and vitamin B12 is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* HR-HPV DNA test positivity

Exclusion Criteria:

* No HSIL

Where this trial is running

Modena, Modena

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HPV Infection

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.