Clinical trial Recruiting at 1 site Interventional Ages 25 to 65 Women only

Using a dietary supplement to prevent HPV infection persistence

Official title: A Pilot Study to Test the Effect of the Association of Epigallocatechin Gallate (EGCG), Folic Acid and Vitamin B12 in Preventing the Persistence of Human Papilloma Virus (HPV) Infection.

Run by Lo.Li.Pharma s.r.l · NCT06285357 · Data updated 2026-11-12

This study tests if a dietary supplement with EGCG, folic acid, and vitamin B12 can help people with cervical HPV infections avoid long-term problems that could lead to cancer.

Quick facts

Study typeInterventional
Ages25 Years to 65 Years
SexWomen only
Enrollment100 (estimated)
SponsorLo.Li.Pharma s.r.l
Industry-sponsored
Locations1 site (Modena, Modena)
StatusRecruiting
StartedFebruary 19, 2024
Main results expectedMarch 2026
Study endsAugust 2026
Registry record updatedNovember 20, 2025
Trial IDNCT06285357 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals who have tested positive for high-risk HPV DNA.

Probably not a fit

Patients who do not have high-grade squamous intraepithelial lesions (HSIL) may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of a dietary supplement containing epigallocatechin gallate (EGCG), folic acid, and vitamin B12 on patients with cervical HPV infections. The goal is to determine whether this combination can help prevent the persistence of HPV, which is known to lead to cervical cancer. Participants will be monitored for changes in HPV status following the intervention. The study aims to provide insights into alternative treatment options for HPV infections.

Why it matters

Potential benefit: If successful, this approach could offer a new preventive strategy against the persistence of HPV infections, potentially reducing the risk of cervical cancer.

How similar studies have gone: While there is ongoing research into dietary supplements for HPV treatment, this specific combination of EGCG, folic acid, and vitamin B12 is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* HR-HPV DNA test positivity

Exclusion Criteria:

* No HSIL

Where it's running

  • Azienda Ospedaliero-Universitaria di Modena
    Modena, Modena, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.