Using a chatbot or genetic counselor for cancer genetic screening in rural areas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to explore how different methods of providing cancer genetic screening can impact the decision-making process for individuals at high risk of gene mutation-related cancers. Participants will be randomly assigned to receive pre-genetic test education either from a genetic counselor or through a Genetic Information Assistant (GIA) chatbot. They will then provide a saliva sample for genetic testing to identify potential cancer gene mutations. The study will compare the rates of genetic testing uptake between the two groups to determine the effectiveness of the GIA compared to traditional counseling methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* At high risk for having a genetic pathogenic variant as assessed by a GC or physician according to the NCCN guidelines
* Provision of signed and dated informed consent form.
* Stated willingness to comply with all study procedures and availability for the duration of the study.
* Male or female, aged 18 and over.
* Subjects must have a smartphone with access to cellular and/or internet service or a computer with internet service.
* Subjects must have technological competency/proficiency to use their Smartphone and/or computer in conjunction with the communication aid GIA.

Exclusion Criteria:

* Cannot communicate in English or Spanish.
* Subjects must not have completed panel-based cancer genetic testing in the past.

Where it's running

• University of Virginia
  Charlottesville, Virginia, United States Recruiting

Study contacts

• Principal investigator: Kari Ring, MD — University of Virginia
• Study coordinator: Evelyn Villalobos
• Email: EV4PD@uvahealth.org
• Phone: (434) 297-4579

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Classifying genetic variants for cancer risk assessment

  This study is testing how to better understand certain genetic changes in cancer-related genes to help patients and their families make informed decisions about their cancer risk and treatment options.

  Recruiting at 55 sites Institut Curie · Bastia, Corsica and 61 other locations · NCT01689584

• Transition outcomes for adolescents and young adults with a cancer predisposition.

  See if young adults with a genetic cancer predisposition establish and keep up care with adult providers and follow recommended cancer surveillance after they leave pediatric care at St. Jude.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT07456904

• How genes and alcohol interact to affect liver cancer risk

  This project will test if certain gene variants together with alcohol use and metabolic problems raise the risk of liver cancer in people with fatty or cryptogenic liver disease, especially men with diabetes or obesity.

  Recruiting Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Milan, Milano · NCT07272200

• Topical 5% minoxidil to boost blood flow and skin‑flap survival during breast reconstruction

  This trial will test whether applying 5% topical minoxidil to one breast before bilateral risk‑reducing mastectomy with immediate reconstruction improves blood flow and skin‑flap survival compared with a placebo on the other breast.

  Recruiting Phase 1 Duke University · Durham, North Carolina · NCT07264790

• Slow-SPEED: Can a smartphone app help people with prodromal Parkinson's stay more active?

  This trial tests whether a remote smartphone app can help people with a LRRK2 G2019S or GBA1 N370S mutation increase daily activity and see if exercise might slow prodromal Parkinson's signs.

  Recruiting Radboud University Medical Center · Rochester, New York and 1 other locations · NCT06993142

• Understanding how genetics and lifestyle affect endometrial cancer recurrence

  This study is trying to see how genetics and lifestyle factors like obesity and diabetes affect the chances of endometrial cancer coming back in patients.

  Recruiting Faculty Hospital Kralovske Vinohrady · Prague · NCT06680791

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.