Using 68Ga-FAPI PET/CT to visualize malignant tumors
Official title: The Diagnostic Efficiency of 68Ga-FAPI PET/CT in Malignant Tumors
Run by Zhongnan Hospital · NCT05034146 · Data updated 2026-11-12
This study is testing a new imaging method using a special agent to see if it can help doctors better spot and understand malignant tumors, especially in gastrointestinal cancers.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 88 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Zhongnan Hospital Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Status | Recruiting |
| Started | February 23, 2021 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | June 5, 2025 |
| Trial ID | NCT05034146 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with suspected or confirmed malignant tumors.
✕Probably not a fit
Patients who are pregnant, planning to become pregnant, or have allergies to multiple drugs may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the use of a novel imaging agent, 68Ga-FAPI, in conjunction with PET/CT scans to enhance the visualization of malignant tumors. The study aims to evaluate the effectiveness of this molecular imaging technique in detecting and characterizing tumors, particularly in gastrointestinal cancers. By targeting fibroblast activation protein (FAP), which is overexpressed in cancer-associated fibroblasts, the trial seeks to provide more accurate diagnostic information compared to traditional imaging methods. The research will involve patients with suspected or confirmed malignant tumors to assess the advantages of this approach over existing imaging modalities.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy and better treatment planning for patients with malignant tumors.
How similar studies have gone: Previous studies have shown favorable diagnostic efficiency for 68Ga-FAPI in small samples, but this trial aims to confirm its advantages in a larger population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Volunteering to participate in clinical trial and sign an informed consent form Patients with suspected or confirmed malignant tumor Exclusion Criteria: Female patients plan to become pregnant within 6 months Pregnant and lactating women Patients are allergic to multiple drugs including test drug Patients have participated in other clinical trials in the past one month
Where it's running
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Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Yong He, MD, PhD — Zhongnan Hospital
- Study coordinator: Yong He, MD, PhD
- Email: vincentheyong@163.com
- Phone: +86-27-67812698
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.