Using 3D Ultrasound for Needle Guidance in Gynecological Cancer Treatment
A Multi-Modality Comparison of Needle Placement During Gynecological Brachytherapy Procedures
NA · Western University, Canada · NCT04705467
This study is testing if using 3D ultrasound can help doctors place needles more accurately during radiation treatment for women with gynecological cancers.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 35 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Western University, Canada (other) |
| Drugs / interventions | radiation |
| Locations | 1 site (London, Ontario) |
| Trial ID | NCT04705467 on ClinicalTrials.gov |
What this trial studies
This study explores the use of 3D ultrasound imaging to guide needle insertion during brachytherapy for gynecological cancers. Brachytherapy is a critical treatment that delivers radiation directly to tumors while minimizing damage to surrounding healthy tissue. The study aims to improve the precision of needle placement in the pelvis, which is currently guided by clinical examination and pre-treatment imaging without standardized methods. By providing real-time imaging, the goal is to enhance treatment outcomes for patients with advanced or recurrent gynecological malignancies.
Who should consider this trial
Good fit: Ideal candidates include females aged 18 and older with locally advanced or recurrent gynecological cancers who are eligible for interstitial or ring and tandem brachytherapy.
Not a fit: Patients who are not offered interstitial brachytherapy as a treatment option will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective brachytherapy treatments with reduced side effects for patients.
How similar studies have performed: While the use of imaging in brachytherapy is established, the specific application of 3D ultrasound for needle guidance in this context is relatively novel and has not been widely tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Females of age eighteen (18) or greater. * Patients with locally advanced or recurrent gynecological malignancies who are offered interstitial or ring and tandem brachytherapy treatment. These typically would include patients with primary or recurrent vaginal cancers, endometrial cancers or cervical cancers. Histologies of these cancers are typically adenocarcinomas or squamous cell carcinomas Exclusion Criteria: • Above patients who are not offered interstitial brachytherapy as a treatment modality
Where this trial is running
London, Ontario
- London Regional Cancer Program, Victoria Hospital — London, Ontario, Canada (RECRUITING)
Study contacts
- Study coordinator: David D'Souza, MD
- Email: David.DSouza@lhsc.on.ca
- Phone: 519-685-8500
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gynecologic Cancer, 3D Ultrasound, Intervention