Using 2% lidocaine gel to reduce pain after hemorrhoid surgery
Efficacy of 2% Lidocaine Gel in Reducing Postoperative Pain and Analgesic Consumption Following Haemorrhoidectomy: A Randomized, Double-Blind, Controlled Trial
This study is testing if a 2% lidocaine gel can help reduce pain after hemorrhoid surgery and lower the need for pain medication.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | E-DA Hospital Academic / other |
| Locations | 1 site (Kaohsiung City) |
| Trial ID | NCT06420388 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of 2% lidocaine gel in alleviating postoperative pain and reducing the need for analgesics following Ferguson haemorrhoidectomy. A total of 222 patients will be randomly assigned to receive either the lidocaine gel or a non-anaesthetic lubricant gel as a control. Pain levels will be measured using a visual analog scale at multiple time points post-surgery, and analgesic consumption will also be tracked. The study aims to determine if lidocaine gel can significantly improve pain management in this surgical context.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older diagnosed with Grade III or IV hemorrhoids who are scheduled for Ferguson haemorrhoidectomy.
Not a fit: Patients with recurrent hemorrhoidal disease or other concurrent anal pathologies, as well as those with certain medical histories, may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could lead to improved pain management and reduced reliance on analgesics for patients recovering from hemorrhoid surgery.
How similar studies have performed: While the specific use of 2% lidocaine gel in this context may be novel, similar studies have shown promising results in pain management with local anesthetics.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Diagnosed with Grade III or IV hemorrhoids * Candidate for Ferguson haemorrhoidectomy Exclusion Criteria: * Not a candidate for Ferguson haemorrhoidectomy * Recurrent hemorrhoidal disease * Concurrent anal pathology diagnosed preoperatively, including: * Anal fistula * Anal fissure * Anal polyp * History of diabetes mellitus * History of liver cirrhosis * History of inflammatory bowel disease * Documented neuropathy * Coagulation disorders * Currently on anticoagulants * Documented allergy to any of the drugs included in the protocol
Where this trial is running
Kaohsiung City
- E-Da hospital — Kaohsiung City, Taiwan (Recruiting)
Study contacts
- Study coordinator: Chen Chih-i
- Email: ed111988@edah.org.tw
- Phone: +886978060015
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.