Using 18F‑choline PET/CT versus ultrasound and sestamibi to locate diseased parathyroid glands

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an open, single-center, prospective, randomized trial comparing 18F‑choline PET/CT to conventional preoperative imaging (neck ultrasonography and 99mTc‑sestamibi scintigraphy) for localization of abnormal parathyroid glands in primary hyperparathyroidism. Adult patients with confirmed pHPT and an indication for parathyroidectomy are randomized to receive either the 18F‑choline PET/CT imaging pathway or the conventional imaging pathway prior to surgery. The study will compare localization accuracy and downstream surgical outcomes such as cure rates, operation time, and complications. The goal is to determine whether more precise imaging can reduce the extent of dissection and improve surgical efficiency and outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Proven primary hyperparathyroidism Indication for surgery Adult (\>18 years)

Exclusion Criteria:

Inability to give informed consent Allergy to contrast Pregnancy and breastfeeding

Where it's running

• Skåne University Hospital
  Lund, Sweden Recruiting

Study contacts

• Study coordinator: Martin Almquist
• Email: martin.almquist@med.lu.se
• Phone: +46-46176245

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.