Clinical trial Recruiting at 1 site Observational Ages 30 to 50 Women only

Urinary incontinence and pelvic floor muscle activity in people with multiple sclerosis

Official title: Identification of Factors Related to Urinary Incontinence in Patients With Multiple Sclerosis and Electromyographic Assessment of Pelvic Floor Muscle Activity: A Cross-Sectional Study

Run by Artvin Coruh University · NCT07236684 · Data updated 2026-11-12

This research will try to see if pelvic floor muscle activity measured by EMG is linked to how severe urinary incontinence is in people with multiple sclerosis.

More Multiple Sclerosis trials

Quick facts

Study typeObservational
Ages30 Years to 50 Years
SexWomen only
Enrollment47 (estimated)
SponsorArtvin Coruh University
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedMarch 9, 2026
Main results expectedSeptember 30, 2026
Study endsSeptember 30, 2026
Registry record updatedMarch 23, 2026
Trial IDNCT07236684 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with multiple sclerosis by the 2017 McDonald criteria who have symptoms of urinary incontinence, EDSS below 6.5, can communicate, and meet the other eligibility rules are ideal candidates.

Probably not a fit

People with recent MS attacks, recent medication changes, pregnancy, recent vaginal or cesarean delivery, pelvic organ prolapse, urinary tract infection, or EDSS ≥6.5 would not be eligible and are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a cross-sectional observational analysis of 47 people with multiple sclerosis who report urinary incontinence. Participants will undergo pelvic floor electromyography (EMG) and complete clinical and patient-reported measures including EDSS, NBSS, ICIQ-SF, IIQ-7, IPAQ, and FSS. The investigators will compare EMG findings with incontinence severity and explore relationships with disability, fatigue, physical activity, and quality-of-life impact. Patients with recent attacks, recent medication changes, pregnancy, recent deliveries, pelvic organ prolapse, or urinary tract infection are excluded to reduce confounding.

Why it matters

Potential benefit: If successful, this work could help identify pelvic floor dysfunction patterns tied to incontinence in MS and guide more targeted pelvic floor therapies.

How similar studies have gone: Previous work has used EMG to describe pelvic floor dysfunction in MS, but direct correlations between specific EMG patterns and incontinence severity are limited, so this study builds on partial prior evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* having an MS diagnosis according to the 2017 revised McDonald criteria,
* experiencing symptoms of UI as defined by the International Continence Society (ICS),
* having an EDSS score below 6.5,
* PwMS with no communication issues.

Exclusion Criteria:

* PwMS who did not give consent to participate,
* those with medication changes in the past 6 months,
* pregnant PwMS,
* recent vaginal or caesarean deliveries within 6 months,
* pelvic organ prolapse,
* urinary tract infection,
* recent attack history in the past month.

Where it's running

  • Prof. Dr. Cemil Taşçıoğlu City Hospital
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.