Updating how we detect frailty in older adults

Update on the Detection of Frailty in Older Adults: A Multicenter Cohort Machine Learning-Based Study

Universidad Europea de Madrid · NCT06218121

This study is testing new ways to identify frailty in older adults by looking at their health and using ultrasound images to see if it can help improve their care and quality of life.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages62 Years and up
SexAll
SponsorUniversidad Europea de Madrid (other)
Locations1 site (Madrid, Outside of the US)
Trial IDNCT06218121 on ClinicalTrials.gov

What this trial studies

This observational study aims to enhance the diagnostic assessment of frailty in older adults by correlating various demographic and functional variables with ultrasound imaging. It will involve a cohort of 500 older adults diagnosed with frailty, focusing on their functional capacity, quality of life, and musculoskeletal symptoms. The study will also utilize Machine Learning to analyze patient profiles and risk factors, ultimately improving treatment strategies and educational programs tailored to individual needs.

Who should consider this trial

Good fit: Ideal candidates for this study are older adults diagnosed with frailty by a geriatric physician.

Not a fit: Patients with severe cognitive impairment or those unable to walk may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and management strategies for frailty in older adults, enhancing their quality of life.

How similar studies have performed: Other studies have shown promise in using ultrasound and Machine Learning for assessing frailty, indicating a potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

A diagnosis of signs and symptoms of frailty by a geriatric physician in the research group will be used as the primary inclusion criterion. Frailty will be assessed and diagnosed using the frailty phenotype and the Clinical Frailty Scale.

Exclusion Criteria:

* Acute myocardial infarction in the last 3 months and/or unstable angina pectoris
* Uncontrolled arrhythmia, recent thromboembolism and terminal illness.
* Patients undergoing MMII unloading or MMSS/MMII fractures in the last three months.
* Patients with a functional gait index of 1 (Inability to walk)
* Severe pain (7/10 VAS)
* Previous neuromuscular pathology presenting with weakness
* Medication that does not allow the patient's actual muscle reaction to be assessed
* Severe cognitive impairment that would prevent collaboration and understanding of the tests to be performed.
* Cardiovascularly unstable patients and uncontrolled arterial hypertension.

Where this trial is running

Madrid, Outside of the US

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Strength, Quality of Life, Functional Independence, Functionality, Pain, Sarcopenia, Anxiety, Kinesiophobia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.