Unified network for a Yale liquid biopsy repository

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

UNIFY is a Yale-wide program that prospectively collects Streck-tube blood samples, dried blood spots, and optional archival tissue from patients with solid tumors or blood cancers across all tumor types. The goal is to create a master repository to enable future liquid biopsy and biomarker research. Participation requires informed consent and HIPAA authorization, with eligibility including confirmed or suspected cancer or a defined high-risk status, and no contraindication to blood collection. The study is observational and does not specify interventions or treatments within this framework. Location is Smilow Cancer Hospital in New Haven, CT, led by Yale University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Histological or radiological evidence of a suspected or confirmed solid tumor or hematologic malignancy, OR an individual identified as high-risk for cancer (based on identified germline aberration in a cancer predisposition gene, hormonal or medical risk factors, and/or significant family history of malignancy).
* Willing and able to provide informed consent and HIPAA authorization for participation in UNIFY.
* If being co-consented for a separate primary research study, the participant must also fulfill the eligibility criteria for that primary research study. Where there is a discrepancy in eligibility criteria between UNIFY and the primary research study, the primary research study's criteria take precedence.

Exclusion Criteria:

* Inability to provide informed consent.
* Any medical contraindication to peripheral venipuncture as judged by the treating physician or research team (e.g., severe coagulopathy or other contraindication to additional research blood draw).

Where it's running

• Smilow Cancer Hospital
  New Haven, Connecticut, United States Recruiting

Study contacts

• Principal investigator: Mitchell Elliott, MD — Yale University
• Study coordinator: Mitchell Elliott, MD
• Email: Mitchell.elliott@yale.edu
• Phone: 475-375-7981

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.