Understanding ventilation quality during in-hospital cardiac arrest
The Ventilation During In-Hospital Cardiac Arrest (VENT-IHCA) Study
This study is testing how different breathing techniques during CPR can help adults who have a cardiac arrest in the hospital survive better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 900 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Aarhus Academic / other |
| Locations | 11 sites (Aabenraa and 10 other locations) |
| Trial ID | NCT06809309 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate how different ventilation parameters during cardiopulmonary resuscitation (CPR) affect short-term survival outcomes in adults experiencing in-hospital cardiac arrest. Researchers will measure ventilation volumes and rates during CPR to determine which combinations are most effective in achieving return of spontaneous circulation (ROSC). By analyzing this data, the study seeks to provide insights that could improve CPR practices and patient outcomes in critical situations.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who experience an in-hospital cardiac arrest and have recorded ventilation data.
Not a fit: Patients with a do-not-attempt cardiopulmonary resuscitation order or those receiving invasive mechanical circulatory support at the time of cardiac arrest may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance CPR techniques, leading to improved survival rates for patients experiencing in-hospital cardiac arrest.
How similar studies have performed: While there have been studies on CPR techniques, this specific focus on ventilation parameters during in-hospital cardiac arrest is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. In-hospital cardiac arrest 2. Age ≥ 18 years 3. \>1minute of recorded ventilation data Exclusion Criteria: 1. Documented do-not-attempt cardiopulmonary resuscitation order 2. Invasive mechanical circulatory support at the time of the cardiac arrest
Where this trial is running
Aabenraa and 10 other locations
- Hospital of Southern Jutland - Aabenraa — Aabenraa, Denmark (Recruiting)
- Aalborg University Hospital — Aalborg, Denmark (Recruiting)
- Aarhus University Hospital — Aarhus, Denmark (Recruiting)
- Hospital of Southwest Jutland - Esbjerg — Esbjerg, Denmark (Recruiting)
- Gødstrup Hospital — Gødstrup, Denmark (Recruiting)
- North Denmark Region Hospital - Hjørring — Hjørring, Denmark (Recruiting)
- Horsens Regional Hospital — Horsens, Denmark (Recruiting)
- Odense University Hospital — Odense, Denmark (Recruiting)
- Randers Regional Hospital — Randers, Denmark (Recruiting)
- Viborg Regional Hospital — Viborg, Denmark (Recruiting)
- St. Olavs Hospital, Trondheim University Hospital — Trondheim, Norway (Recruiting)
Study contacts
- Principal investigator: Johannes Wittig, MD — Department of Clinical Medicine, Aarhus University, Denmark; Department of Medicine, Randers Regional Hospital, Randers, Denmark; Research Center for Emergency Medicine, Aarhus University Hospital, Denmark
- Study coordinator: Johannes Wittig, MD
- Email: johannes.wittig@clin.au.dk
- Phone: +45 78 42 00 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.