Clinical trial Recruiting at 11 sites Observational Ages 18 and up

Understanding ventilation quality during in-hospital cardiac arrest

Official title: The Ventilation During In-Hospital Cardiac Arrest (VENT-IHCA) Study

Run by University of Aarhus · NCT06809309 · Data updated 2026-11-12

This study is testing how different breathing techniques during CPR can help adults who have a cardiac arrest in the hospital survive better.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment900 (estimated)
SponsorUniversity of Aarhus
Academic / other
Locations11 sites (Aabenraa and 10 other locations)
StatusRecruiting
StartedFebruary 1, 2025
Main results expectedApril 2027
Study endsJune 2027
Registry record updatedMarch 30, 2026
Trial IDNCT06809309 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who experience an in-hospital cardiac arrest and have recorded ventilation data.

Probably not a fit

Patients with a do-not-attempt cardiopulmonary resuscitation order or those receiving invasive mechanical circulatory support at the time of cardiac arrest may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate how different ventilation parameters during cardiopulmonary resuscitation (CPR) affect short-term survival outcomes in adults experiencing in-hospital cardiac arrest. Researchers will measure ventilation volumes and rates during CPR to determine which combinations are most effective in achieving return of spontaneous circulation (ROSC). By analyzing this data, the study seeks to provide insights that could improve CPR practices and patient outcomes in critical situations.

Why it matters

Potential benefit: If successful, this study could enhance CPR techniques, leading to improved survival rates for patients experiencing in-hospital cardiac arrest.

How similar studies have gone: While there have been studies on CPR techniques, this specific focus on ventilation parameters during in-hospital cardiac arrest is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. In-hospital cardiac arrest
2. Age ≥ 18 years
3. \>1minute of recorded ventilation data

Exclusion Criteria:

1. Documented do-not-attempt cardiopulmonary resuscitation order
2. Invasive mechanical circulatory support at the time of the cardiac arrest

Where it's running

  • Hospital of Southern Jutland - Aabenraa
    Aabenraa, Denmark
    Recruiting
  • Aalborg University Hospital
    Aalborg, Denmark
    Recruiting
  • Aarhus University Hospital
    Aarhus, Denmark
    Recruiting
  • Hospital of Southwest Jutland - Esbjerg
    Esbjerg, Denmark
    Recruiting
  • Gødstrup Hospital
    Gødstrup, Denmark
    Recruiting
  • North Denmark Region Hospital - Hjørring
    Hjørring, Denmark
    Recruiting
Show 5 more locations
  • Horsens Regional Hospital
    Horsens, Denmark
    Recruiting
  • Odense University Hospital
    Odense, Denmark
    Recruiting
  • Randers Regional Hospital
    Randers, Denmark
    Recruiting
  • Viborg Regional Hospital
    Viborg, Denmark
    Recruiting
  • St. Olavs Hospital, Trondheim University Hospital
    Trondheim, Norway
    Recruiting

Study contacts

  • Principal investigator: Johannes Wittig, MD — Department of Clinical Medicine, Aarhus University, Denmark; Department of Medicine, Randers Regional Hospital, Randers, Denmark; Research Center for Emergency Medicine, Aarhus University Hospital, Denmark
  • Study coordinator: Johannes Wittig, MD
  • Email: johannes.wittig@clin.au.dk
  • Phone: +45 78 42 00 00

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.