Understanding ventilation quality during in-hospital cardiac arrest
Official title: The Ventilation During In-Hospital Cardiac Arrest (VENT-IHCA) Study
Run by University of Aarhus · NCT06809309 · Data updated 2026-11-12
This study is testing how different breathing techniques during CPR can help adults who have a cardiac arrest in the hospital survive better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 900 (estimated) |
| Sponsor | University of Aarhus Academic / other |
| Locations | 11 sites (Aabenraa and 10 other locations) |
| Status | Recruiting |
| Started | February 1, 2025 |
| Main results expected | April 2027 |
| Study ends | June 2027 |
| Registry record updated | March 30, 2026 |
| Trial ID | NCT06809309 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who experience an in-hospital cardiac arrest and have recorded ventilation data.
✕Probably not a fit
Patients with a do-not-attempt cardiopulmonary resuscitation order or those receiving invasive mechanical circulatory support at the time of cardiac arrest may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate how different ventilation parameters during cardiopulmonary resuscitation (CPR) affect short-term survival outcomes in adults experiencing in-hospital cardiac arrest. Researchers will measure ventilation volumes and rates during CPR to determine which combinations are most effective in achieving return of spontaneous circulation (ROSC). By analyzing this data, the study seeks to provide insights that could improve CPR practices and patient outcomes in critical situations.
Why it matters
Potential benefit: If successful, this study could enhance CPR techniques, leading to improved survival rates for patients experiencing in-hospital cardiac arrest.
How similar studies have gone: While there have been studies on CPR techniques, this specific focus on ventilation parameters during in-hospital cardiac arrest is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. In-hospital cardiac arrest 2. Age ≥ 18 years 3. \>1minute of recorded ventilation data Exclusion Criteria: 1. Documented do-not-attempt cardiopulmonary resuscitation order 2. Invasive mechanical circulatory support at the time of the cardiac arrest
Where it's running
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Hospital of Southern Jutland - Aabenraa
Aabenraa, Denmark Recruiting -
Aalborg University Hospital
Aalborg, Denmark Recruiting -
Aarhus University Hospital
Aarhus, Denmark Recruiting -
Hospital of Southwest Jutland - Esbjerg
Esbjerg, Denmark Recruiting -
Gødstrup Hospital
Gødstrup, Denmark Recruiting -
North Denmark Region Hospital - Hjørring
Hjørring, Denmark Recruiting
Show 5 more locations
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Horsens Regional Hospital
Horsens, Denmark Recruiting -
Odense University Hospital
Odense, Denmark Recruiting -
Randers Regional Hospital
Randers, Denmark Recruiting -
Viborg Regional Hospital
Viborg, Denmark Recruiting -
St. Olavs Hospital, Trondheim University Hospital
Trondheim, Norway Recruiting
Study contacts
- Principal investigator: Johannes Wittig, MD — Department of Clinical Medicine, Aarhus University, Denmark; Department of Medicine, Randers Regional Hospital, Randers, Denmark; Research Center for Emergency Medicine, Aarhus University Hospital, Denmark
- Study coordinator: Johannes Wittig, MD
- Email: johannes.wittig@clin.au.dk
- Phone: +45 78 42 00 00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.