Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding tumor evolution in early-stage non-small cell lung cancer

Official title: A Multiomics Study of Tumor Evolution Characteristics and Prognostic Model in Early-stage Non-small Cell Lung Cancer

Run by Peking University People's Hospital · NCT05352035 · Data updated 2026-11-12

This study is trying to understand how early-stage non-small cell lung cancer changes over time by looking at tumor samples and DNA to help improve treatment and monitoring for patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorPeking University People's Hospital
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedApril 20, 2022
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedApril 30, 2025
Trial IDNCT05352035 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with early-stage NSCLC who have undergone radical surgical resection.

Probably not a fit

Patients with a history of other malignant tumors or evidence of distant metastasis prior to surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the evolutionary mechanisms of early-stage non-small cell lung cancer (NSCLC) through multiomics analysis. By analyzing tumor tissue and circulating tumor DNA, the study seeks to establish a prognostic model and a recurrence monitoring system. The findings could enhance the management of lung cancer patients and improve their overall prognosis. The study will utilize available clinical-pathologic data, imaging data, and follow-up information to support its objectives.

Why it matters

Potential benefit: If successful, this study could lead to improved prognostic models and monitoring systems for early-stage NSCLC patients.

How similar studies have gone: While multiomics approaches are gaining traction, this specific study's focus on early-stage NSCLC and its prognostic implications is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 18 years old;
2. Early-stage NSCLC patients underwent radical surgical resection;
3. Sufficient tumor tissue and blood sample for study use;
4. Available clinical-pathologic data, imaging data and follow-up date;
5. Written informed consent.

Exclusion Criteria:

1. History of other malignant tumors;
2. Evidence of distant metastasis before surgery;
3. Insufficient tumor tissue or blood sample for study use;
4. Clinical-pathologic data, imaging data or follow-up date is not available;
5. Other judgments by the Investigator that the patient should not participate in the study.

Where it's running

  • Peking University People's Hospital
    Beijing, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.