Clinical trial Recruiting at 1 site Observational Ages 18 to 55 Women only

Understanding the risk factors for adenomyosis progression

Official title: Risk Factors Associated With The Progression Of Adenomyosis

Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06718088 · Data updated 2026-11-12

This study is trying to find out what factors might make adenomyosis worse over time in women aged 18 to 55 who show signs of the condition on ultrasound.

Quick facts

Study typeObservational
Ages18 Years to 55 Years
SexWomen only
Enrollment258 (estimated)
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Academic / other
Locations1 site (Bologna)
StatusRecruiting
StartedJune 1, 2022
Main results expectedJune 1, 2026
Study endsJune 1, 2026
Registry record updatedDecember 5, 2024
Trial IDNCT06718088 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 18 to 55 with ultrasound-confirmed signs of adenomyosis.

Probably not a fit

Patients who have undergone hysterectomy or have recent pregnancy or childbirth may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the risk factors associated with the progression of adenomyosis, a common gynecological disorder affecting women of childbearing age. Utilizing transvaginal ultrasound (TVUS) as the primary diagnostic tool, the study will assess the natural course of adenomyosis and identify factors that may influence its progression over time. Participants will be women aged 18 to 55 who exhibit specific ultrasound signs of adenomyosis, and the study will gather data to enhance understanding of this condition.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for women suffering from adenomyosis.

How similar studies have gone: While there have been studies on hormonal treatments for adenomyosis, this investigation into the progression and risk factors is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged between 18 and 55 years;
* Presence of at least two direct and indirect signs according to the MUSA classification
* Obtaining informed consent

Exclusion Criteria:

* Patients undergoing hysterectomy;
* Virgo patients;
* Patients reporting intolerance to transvaginal ultrasound;
* Gynaecological oncology;
* Recent pregnancy or childbirth (within 6 months)

Where it's running

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna
    Bologna, Italy
    Recruiting

Study contacts

  • Principal investigator: Paolo Casadio, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
  • Study coordinator: Paolo Casadio, MD
  • Email: paolo.casadio@aosp.bo.it
  • Phone: +390512144411

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.