Understanding the risk factors for adenomyosis progression

Risk Factors Associated With The Progression Of Adenomyosis

Observational IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06718088

This study is trying to find out what factors might make adenomyosis worse over time in women aged 18 to 55 who show signs of the condition on ultrasound.

Quick facts

Study typeObservational
Enrollment258 (estimated)
Ages18 Years to 55 Years
SexFemale
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other
Locations1 site (Bologna)
Trial IDNCT06718088 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the risk factors associated with the progression of adenomyosis, a common gynecological disorder affecting women of childbearing age. Utilizing transvaginal ultrasound (TVUS) as the primary diagnostic tool, the study will assess the natural course of adenomyosis and identify factors that may influence its progression over time. Participants will be women aged 18 to 55 who exhibit specific ultrasound signs of adenomyosis, and the study will gather data to enhance understanding of this condition.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 to 55 with ultrasound-confirmed signs of adenomyosis.

Not a fit: Patients who have undergone hysterectomy or have recent pregnancy or childbirth may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for women suffering from adenomyosis.

How similar studies have performed: While there have been studies on hormonal treatments for adenomyosis, this investigation into the progression and risk factors is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged between 18 and 55 years;
* Presence of at least two direct and indirect signs according to the MUSA classification
* Obtaining informed consent

Exclusion Criteria:

* Patients undergoing hysterectomy;
* Virgo patients;
* Patients reporting intolerance to transvaginal ultrasound;
* Gynaecological oncology;
* Recent pregnancy or childbirth (within 6 months)

Where this trial is running

Bologna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Adenomyosisadenomyosisrisk factorstransvaginal ultrasound
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.