Understanding the risk factors for adenomyosis progression
Official title: Risk Factors Associated With The Progression Of Adenomyosis
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06718088 · Data updated 2026-11-12
This study is trying to find out what factors might make adenomyosis worse over time in women aged 18 to 55 who show signs of the condition on ultrasound.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 55 Years |
| Sex | Women only |
| Enrollment | 258 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna) |
| Status | Recruiting |
| Started | June 1, 2022 |
| Main results expected | June 1, 2026 |
| Study ends | June 1, 2026 |
| Registry record updated | December 5, 2024 |
| Trial ID | NCT06718088 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18 to 55 with ultrasound-confirmed signs of adenomyosis.
✕Probably not a fit
Patients who have undergone hysterectomy or have recent pregnancy or childbirth may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the risk factors associated with the progression of adenomyosis, a common gynecological disorder affecting women of childbearing age. Utilizing transvaginal ultrasound (TVUS) as the primary diagnostic tool, the study will assess the natural course of adenomyosis and identify factors that may influence its progression over time. Participants will be women aged 18 to 55 who exhibit specific ultrasound signs of adenomyosis, and the study will gather data to enhance understanding of this condition.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for women suffering from adenomyosis.
How similar studies have gone: While there have been studies on hormonal treatments for adenomyosis, this investigation into the progression and risk factors is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 55 years; * Presence of at least two direct and indirect signs according to the MUSA classification * Obtaining informed consent Exclusion Criteria: * Patients undergoing hysterectomy; * Virgo patients; * Patients reporting intolerance to transvaginal ultrasound; * Gynaecological oncology; * Recent pregnancy or childbirth (within 6 months)
Where it's running
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IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy Recruiting
Study contacts
- Principal investigator: Paolo Casadio, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Paolo Casadio, MD
- Email: paolo.casadio@aosp.bo.it
- Phone: +390512144411
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.