Understanding the prognosis of heart transplant patients with heart failure
Prognosis of Heart Transplanted Patients With Heart Failure (RE-START): a National Multi-center, Retrospective-prospective, Cohort Study
This study looks at heart transplant patients with heart failure to see how different causes of their condition affect their recovery and long-term health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 3 Years to 80 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT05775432 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the prognosis of patients who have undergone heart transplantation due to various causes of heart failure. It will collect clinical data and biological samples from these patients to identify risk factors that influence their outcomes post-transplant. By employing advanced techniques, the study seeks to develop a prognostic prediction model that can guide individualized treatment strategies for improving patient care. The focus is on understanding the differences in prognosis based on the etiology of heart failure and the complications that may arise after transplantation.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with end-stage heart failure who are being evaluated for heart transplantation.
Not a fit: Patients who refuse to sign the informed consent form will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved individualized treatment plans for heart transplant patients, enhancing their survival and quality of life.
How similar studies have performed: Other studies have shown varying success in understanding prognosis in heart transplant patients, but this approach aims to provide a more comprehensive and individualized analysis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with end-stage heart failure presented to our hospital who are evaluated by clinicians and ethically approved for heart transplantation * Individuals whose hearts are donated Exclusion Criteria: * Patients refuse to sign informed consent form
Where this trial is running
Xi'an, Shaanxi
- First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Principal investigator: Guoliang Li — First Affiliated Hospital Xi'an Jiaotong University
- Study coordinator: Guoliang Li
- Email: liguoliang_med@163.com
- Phone: +8613759982523
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.