Understanding the impact of fat around the kidneys in patients having kidney surgery
Znaczenie Kliniczne Przywierającego Tłuszczu Okołonerkowego U Pacjentów Poddawanych Resekcji Guza Nerki
This study looks at how fat around the kidneys affects people having surgery for kidney tumors to see if it influences their recovery and overall health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre of Postgraduate Medical Education Academic / other |
| Locations | 1 site (Otwock) |
| Trial ID | NCT05887245 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the clinical significance of adherent perinephric fat (APF) in patients undergoing partial nephrectomy for kidney tumors. It will identify risk factors for APF occurrence and evaluate its effects on functional, perioperative, and oncological outcomes. Patients eligible for surgery will have blood samples collected prior to the procedure to assess various health parameters, and data will be gathered from medical records and during follow-up periods. The study seeks to enhance understanding of APF and its implications for surgical outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are scheduled for partial nephrectomy due to kidney tumors classified as cT1a-cT1b.
Not a fit: Patients with recurrent kidney cancer or those who have had previous kidney surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical strategies and outcomes for patients undergoing partial nephrectomy.
How similar studies have performed: While the phenomenon of adherent perinephric fat is recognized, this specific study approach is novel and has not been extensively tested in prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients qualified for partial nephrectomy by open, laparoscopic, or robotic method * Tumor stage cT1a-cT1b according to Tumour Node Metastasis classification * Age ≥ 18 years * Written consent to participate in the study Exclusion Criteria: * Patient does not give consent to participate in the study * Patients with recurrent kidney cancer, or who have undergone other surgeries within the kidney * Lack of preoperative imaging available for assessment * Missing medical documentation that prevents data analysis
Where this trial is running
Otwock
- European Health Centre, Second Department of Urology, Centre of Postgraduate Medical Education — Otwock, Poland (Recruiting)
Study contacts
- Principal investigator: Sławomir Poletajew, Prof. — Second Department of Urology, Centre of Postgraduate Medical Education
- Study coordinator: Sławomir Poletajew, Prof.
- Email: slawomir.poletajew@cmkp.edu.pl
- Phone: 22 56 90 148
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.