Understanding the effects of sarcopenic obesity in older adults
Official title: Molecular Mechanisms Underpinning Sarcopenic Obesity
Run by The Swedish School of Sport and Health Sciences · NCT06120647 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study looks at how sarcopenic obesity affects muscle and blood health in older adults compared to those who are just obese or lean.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | The Swedish School of Sport and Health Sciences Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT06120647 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are older adults with sarcopenic obesity who can walk without assistance and meet specific body fat percentage criteria.
✕Probably not a fit
Patients with significant comorbidities or those on certain medications that affect metabolism may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the complex relationship between sarcopenic obesity, obesity, and sarcopenia in older adults. It aims to assess how sarcopenic obesity affects muscle and blood parameters compared to non-sarcopenic obese and lean older individuals. By analyzing these differences, the study seeks to provide insights into the metabolic challenges faced by this population. Participants will be evaluated based on specific inclusion and exclusion criteria to ensure a focused analysis.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management strategies for sarcopenic obesity in older adults.
How similar studies have gone: While there is limited research specifically on sarcopenic obesity, related studies on obesity and sarcopenia have shown promising results, indicating potential for success in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Body fat % in accordance with previously defined criteria * Free of smoking (since 10 years) * Able to walk without assistance * Able to perform bilateral leg extension exercise Exclusion Criteria: * History of or present disease of myocardial, vascular, endocrine, hepatic, renal, pulmonary or neuromuscular origin * Uncontrolled hypo/hypertension * Use of anticoagulants (Warfarin, Trombyl) * Use of metformin or other anti-diabetic medications * Poor appetite and unexplained weight loss (4,5 kg) over the past 6 months * Active malignancy * Present infection * Dementia or delirium * Other conditions that may interfere with the study protocol in the opinion of the PI
Where it's running
-
The Swedish School of Sport and Health Sciences
Stockholm, Sweden Recruiting
Study contacts
- Principal investigator: William Apró, PhD — The Swedish School of Sport and Health Sciences and Karolinska Institute, Stockholm Sweden
- Study coordinator: William Apró, PhD
- Email: william.apro@gih.se
- Phone: 08-120 538 67
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.