Understanding the causes and risk factors of GERD in Xiamen City

Epidemiological Studies and Risk Factor Analysis of Gastroesophageal Reflux Diseases in Xiamen City: a Multicenter Cross-sectional Study

Zhongshan Hospital (Xiamen), Fudan University · NCT06585176

This study is trying to find out what causes GERD and what risk factors are involved for people in Xiamen City who have reflux symptoms.

Quick facts

Study typeObservational
Enrollment1600 (estimated)
Ages16 Years to 75 Years
SexAll
SponsorZhongshan Hospital (Xiamen), Fudan University (other)
Locations1 site (Xiamen, Fujian)
Trial IDNCT06585176 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the epidemiology and risk factors associated with Gastroesophageal Reflux Disease (GERD) in Xiamen City, China. It will involve a specialized cohort of patients who have experienced typical reflux symptoms and will utilize questionnaires to gather data on their conditions. The study emphasizes a biopsychosocial approach, considering both psychological and physical factors that may influence GERD. By establishing a comprehensive understanding of GERD's etiology, the research seeks to inform tailored prevention and treatment strategies for the local population.

Who should consider this trial

Good fit: Ideal candidates for this study are permanent residents of Xiamen who have experienced typical reflux symptoms for at least two days per week.

Not a fit: Patients with severe comorbid conditions or those who have undergone gastrectomy will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for GERD, enhancing patients' quality of life.

How similar studies have performed: While there is limited national epidemiological data on GERD in China, similar studies in other regions have successfully identified risk factors and improved treatment approaches.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients had experienced typical reflux symptoms, i.e., mild heartburn and/or regurgitation symptoms, for at least 2 days per week or moderate/severe reflux symptoms for more than 1 day per week during the previous 3 months and had upper endoscopy examinations in the previous month.
* Cooperate with the questionnaire survey.
* Volunteer and sign the informed consent form.
* Permanent residents in Xiamen.

Exclusion Criteria:

* Malignant tumor.
* Partial or total gastrectomy.
* Failing to cooperate with the investigation because of the factors such as education level and language intelligence disorder, etc.
* Patients with severe heart, lung, kidney, liver, blood, nerve, endocrine and mental system diseases.
* Patients with mental retardation, etc.

Where this trial is running

Xiamen, Fujian

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Gastroesophageal Reflux Disease, Epidemiology, Risk Factors, Gastroesophageal reflux diseases, Barrett esophageal

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.