Understanding survival and factors affecting squamous cell carcinoma of the nasal vestibule

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the survival rates and prognostic factors in patients who have undergone surgical treatment for primary squamous cell carcinoma of the nasal vestibule. It will collect data on patient demographics, tumor characteristics, and surgical details, and will analyze these factors to determine their influence on overall survival, disease-specific survival, and disease-free survival. Participants will be followed for a minimum of 6 months post-surgery, with the goal of potentially developing a new staging system to improve upon existing classifications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosis of squamous cell carcinoma of the nasal vestibule
* underwent upfront surgical treatment with curative intent
* availability of clinical and radiological data for cT reassessment
* availability of histological samples for pT reassessment
* follow-up of at least 6 months after surgery.

Exclusion Criteria:

* patients initially referred for disease persistence or recurrence
* patients affected by tumour involving the nasal vestibule but originating from other sites (eg. nasal cavities, skin of the nasal pyramid or upper lip)

Where it's running

• Centre Hospitalier Universitaire de Toulouse
  Toulouse, Touluse, France Recruiting
• Humanitas Research Hospital
  Rozzano, Milan, Italy Recruiting
• Cagliari University Hospital
  Cagliari, Italy Recruiting
• IRCCS San Raffaele Hospital
  Milan, Italy Recruiting
• Varese University Hospital
  Varese, Italy Recruiting
• Sheffield Teaching Hospital NHS Foundation Trust
  Sheffield, United Kingdom Recruiting

Study contacts

• Principal investigator: Fabio Ferreli, MD — Humanitas Research Hospital IRCCS, Rozzano-Milan
• Study coordinator: Francesca Pirola, MD
• Email: francesca.pirola@humanitas.it
• Phone: 00390282243557

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.