Understanding sound localization in deaf individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project aims to characterize mismatch negativity (MMN) as a neuronal marker for sound localization deficits in individuals with single-sided deafness and those with bilateral profound deafness who have received cochlear implants. The study involves various electro-physiological and psychoacoustic assessments, including EEG evaluations of MMN, spatial localization abilities, and speech recognition performance in noise. Participants include those with normal hearing, single-sided deafness, and cochlear implant recipients, with the goal of understanding how these conditions affect auditory processing and quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For symmetrical hearing subjects:

* Affiliation to a social security
* Normal hearing, or mild to moderate symmetrical hearing loss controlled by tone audiometry performed before inclusion (in air conduction and bone conduction, frequencies 250 Hz to 4000 Hz).
* Signature of the consent form

For subjects with single-sided deafness:

* Affiliation to a social security
* Subject having a unilateral deafness controlled by pure-tone audiometry before inclusion (in air conduction and bone conduction, frequencies 250 Hz to 4000 Hz).
* Signature of the consent form

For subjects with Cochlear Implants:

* Affiliation to a social security
* Subject with symmetrical or asymmetrical profound deafness treated by unilateral cochlear implantation.
* Signature of the consent form

Exclusion Criteria:

* History of associated neurological disorder
* Taking psychotropic drugs
* Persons with complicated social or medical situations

Where it's running

• Oto rhino laryngologie
  Toulouse, France Recruiting

Study contacts

• Principal investigator: Mathieu Marx, PU-PH — CHU Toulouse
• Study coordinator: Soumia TAOUI
• Email: taoui.s@chu-toulouse.fr
• Phone: 0561777704

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Customizing cochlear implant programming based on inner ear nerve health

  This study tests whether tailoring cochlear implant programming to how healthy different parts of the hearing nerve are can improve understanding of speech in noisy environments.

  Recruiting Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT07683689

• Long-term hearing and speech outcomes after cochlear implants

  This project will see if cochlear implants improve hearing, speech understanding, and quality of life in Mandarin-speaking patients of all ages before and after surgery.

  Recruiting Eye & ENT Hospital of Fudan University · Shanghai · NCT07380269

• Reducing follow-up visits for cochlear implant patients using a new mapping strategy

  This study is testing a new way to program cochlear implants to see if adults can have fewer follow-up visits while still feeling satisfied and hearing well.

  Recruiting Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT06960616

• Cisplatin-related (Ear) Hearing Loss and Balance Issues in Head and Neck Cancer Patients

  This observational study tests whether hearing loss, tinnitus, and balance problems occur in head and neck cancer patients treated with cisplatin chemoradiotherapy compared with those receiving only radiotherapy, including optional genetic tests for susceptibility.

  Recruiting Paracelsus Medical University · Nuremberg, Bavaria · NCT06929468

• Early hearing loss detection in a memory clinic

  This project uses a VRB speech-in-noise test to try to detect hearing problems in people with mild to moderate cognitive impairment seen at a memory clinic.

  Recruiting University Hospital, Lille · Lille · NCT06088953

• Understanding how cochlear implants affect hearing in children and adults

  This study is trying to see how cochlear implants help both children and adults hear better and how they adjust to the changes over time.

  Recruiting at 2 sites Massachusetts Eye and Ear Infirmary · Boston, Massachusetts and 1 other locations · NCT05867173

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.