Understanding repetitive anaphylactic reactions in food allergic patients
Prospective Survey of the Repeated Occurrence of Anaphylactic Reactions in Patients with Food Allergies
This study is trying to understand how often people with food allergies have repeated severe allergic reactions and how their experiences affect their daily lives and management of their allergies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 322 (estimated) |
| Sex | All |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 1 site (Berlin, State of Berlin) |
| Trial ID | NCT06192914 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the frequency of repetitive anaphylactic reactions in patients with food allergies, specifically focusing on different elicitors such as peanuts, tree nuts, and legumes. Participants will complete questionnaires at baseline and at 3, 6, 12, and 24 months to provide data on new allergic reactions, eating behaviors, and quality of life related to their food allergies. The study seeks to establish patterns in reactions and assess the impact of previous anaphylactic experiences on patients' self-management and emergency medication use. The ultimate goal is to enhance care strategies to reduce the risk of repeat reactions in food allergic individuals.
Who should consider this trial
Good fit: Ideal candidates include individuals who have experienced an anaphylactic reaction to specific food allergens such as peanuts, tree nuts, or legumes within the past year.
Not a fit: Patients who have not experienced an anaphylactic reaction or do not have a diagnosed food allergy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for food allergic patients, reducing the incidence of repeat anaphylactic reactions.
How similar studies have performed: While this study focuses on a specific aspect of food allergies, similar observational studies have shown success in understanding allergic reactions and improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * anaphylactic reaction to peanuts, other legumes, tree nuts, seeds (e.g. sesame seed, sunflower seed), cereals (e.g. wheat, oat) or pseudocereals (e.g. quinoa) * participation in the European Anaphylaxis Registry (Clinical Trials Identifier: NCT05210543) * possibility and consent to receive links to the follow-up electronic surveys via e-mail and fill out the questionnaires electronically Exclusion Criteria: * if inclusion criteria are fulfilled there are no further exclusion criteria
Where this trial is running
Berlin, State of Berlin
- Charité - Universitätsmedizin Berlin — Berlin, State of Berlin, Germany (Recruiting)
Study contacts
- Principal investigator: Margitta Worm, MD — Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité Universitätsmedizin Berlin
- Study coordinator: Margitta Worm, MD
- Email: sekreteriat-worm@charite.de
- Phone: +49 30 450 518 105
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.