Understanding quality of life and outcomes in anal cancer patients
Official title: ANCA II - Quality of Life and Functional Outcome in Patients With Anal Cancer
Run by Sahlgrenska University Hospital · NCT04792892 · Data updated 2026-11-12
This study looks at how anal cancer affects patients' quality of life and health outcomes from diagnosis through treatment to see what challenges they face.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Sahlgrenska University Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Gothenburg) |
| Status | Recruiting |
| Started | August 1, 2021 |
| Main results expected | April 1, 2025 |
| Study ends | April 1, 2035 |
| Registry record updated | December 8, 2023 |
| Trial ID | NCT04792892 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have been diagnosed with anal squamous carcinoma within the last two months.
✕Probably not a fit
Patients who are unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients diagnosed with anal cancer to assess their quality of life and functional outcomes. It aims to track patients from the point of diagnosis, monitoring early treatment toxicity and long-term morbidity following chemotherapy and radiotherapy. By utilizing questionnaires, the study seeks to gather comprehensive data on the experiences and challenges faced by these patients throughout their treatment journey.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the quality of life and long-term effects of treatment for anal cancer patients, potentially guiding future care strategies.
How similar studies have gone: While there have been studies on quality of life in cancer patients, this specific focus on anal cancer outcomes is relatively novel and underexplored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Anal squamous carcinoma diagnosed within the last 2 months Exclusion Criteria: -No informed consent
Where it's running
-
Dept. of Surgery, Sahlgrenska University Hospital/Ostra
Gothenburg, Sweden Recruiting
Study contacts
- Study coordinator: Eva Angenete
- Email: eva.angenete@vgregion.se
- Phone: 0760514441
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Retifanlimab after chemoradiation for anal cancer
This study tests whether retifanlimab can help people with anal squamous cell carcinoma who have completed chemoradiation and still have residual disease.
-
Irreversible Electroporation for Recurrent Pelvic Tumors
This study tests whether using irreversible electroporation (IRE) is safe and helps control recurrent pelvic tumors in adults who can’t have other local treatments.
-
HPV DNA-guided chemoradiation with Retifanlimab for locally advanced anal cancer
This study tests whether adjusting chemoradiation doses based on HPV ctDNA results and adding Retifanlimab after CRT can improve outcomes for adults with new, locally advanced anal cancer.
-
Gynecological and sexual health after radiotherapy for anal cancer.
See if vaginal problems and changes in sexual health are linked to radiation dose in women treated with chemoradiotherapy for anal cancer 6–36 months after treatment.
-
Self-sampling to improve anal lesion outcomes
This study will test whether people at higher risk for anal cancer will use a self-collected anal swab and whether that increases follow-up cytology and high-resolution anoscopy (HRA) appointment attendance.
-
Testing trastuzumab deruxtecan (T‑DxD) for HER2‑positive advanced solid tumors
This will test whether trastuzumab deruxtecan (T‑DxD) helps adults in the US with HER2‑positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have had prior systemic treatment and have no satisfactory alternative options.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.