Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Understanding Quality of Life After Ischemic Stroke in Young Adults

Official title: Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults: a Prospective Observational Study in Young Ischemic Stroke Patients Under 50 Years

Run by Palacky University · NCT04839887 · Data updated 2026-11-12

This study looks at how different factors affect the quality of life for young adults under 50 who have had an ischemic stroke to see what helps them recover better over the first year.

More Ischemic Stroke trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment520 (estimated)
SponsorPalacky University
Academic / other
Locations1 site (Olomouc)
StatusRecruiting
StartedMarch 1, 2021
Main results expectedDecember 31, 2025
Study endsDecember 31, 2026
Registry record updatedApril 4, 2024
Trial IDNCT04839887 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are young adults aged 18-65 who have suffered an acute ischemic stroke.

Probably not a fit

Patients with transient ischemic attacks, hemorrhagic strokes, severe cognitive impairments, or significant communication disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify factors that affect the quality of life in young adults under 50 years old who have experienced an ischemic stroke. It will assess various predictors of health-related quality of life and evaluate changes over the first year of recovery using standardized neuropsychological tools and specific health-related quality of life measures. The study will involve two phases, starting with the validation of the Czech version of the Stroke Impact Scale 3.0 with 300 participants, followed by a deeper analysis with 200 enrolled patients. The approach combines both qualitative and quantitative research methods to gain comprehensive insights.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation and self-management programs for young ischemic stroke survivors, enhancing their quality of life.

How similar studies have gone: While there have been studies focusing on stroke recovery, this specific approach targeting young ischemic stroke patients and their unique challenges is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Acute ischemic stroke
* Age 18-65 years

Exclusion Criteria:

* Transient ischemic attack without progression to ischemic stroke
* Haemorrhagic stroke
* Severe cognitive impairment
* Severe communication disorder (sensory aphasia with the inability to understand having been verified by a certified speech therapist)
* Concomitant severe systemic illness
* Impaired ability to understand the questionnaires

Where it's running

  • Palacky University, Faculty of Health Sciences
    Olomouc, Czechia
    Recruiting

Study contacts

  • Principal investigator: Elena Gurkova, PhD — Palacky University, Faculty of Health Sciences, Department of Nursing
  • Study coordinator: Elena Gurkova, PhD
  • Email: elena.gurkova@upol.cz
  • Phone: +420585632825

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Remote ischemic conditioning for post-stroke insomnia

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  • Ear-based nerve stimulation to help sleep after a stroke

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    Recruiting Casa Colina Hospital and Centers for Healthcare · Pomona, California · NCT07858656

  • Theta Burst Stimulation to Help Stroke Recovery (Upper and Lower Limbs)

    This trial tests whether applying theta burst stimulation to the motor cortex, in combination with standard rehabilitation, helps people over 45 who recently had a first ischemic stroke recover arm and leg movement.

    Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle · NCT07834333

  • Preventing another ischemic stroke with a smart bracelet and app

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  • Photon-counting CT to check intracranial stents

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.