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Clinical trial No longer in our active list Observational Ages 12 to 70

Understanding Porto-sinusoidal Vascular Disease in India

Official title: Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India

Run by Post Graduate Institute of Medical Education and Research, Chandigarh · NCT06054451 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is trying to see if a new way to classify a liver condition called Porto-sinusoidal Vascular Disease can help better understand and diagnose patients in India who have Non-Cirrhotic Portal Hypertension.

Quick facts

Study typeObservational
Ages12 Years to 70 Years
SexAll
Enrollment210 (estimated)
SponsorPost Graduate Institute of Medical Education and Research, Chandigarh
Academic / other
Locations1 site (Sector-12, Chandigarh)
Trial IDNCT06054451 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients aged 12-70 years, of any gender, with a clinical, pathological, or radiological diagnosis of Non-Cirrhotic Portal Hypertension.

Probably not a fit

Patients with cirrhosis or active malignancy will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to re-evaluate patients diagnosed with Non-Cirrhotic Portal Hypertension (NCPH) in India and determine the applicability of a new histological classification for Porto-sinusoidal Vascular Disease (PSVD). It will involve screening patients based on liver biopsy, endoscopy, and radiology reports to identify those fitting the PSVD diagnosis. The study will compare cohorts diagnosed with INCPH against those meeting the new PSVD criteria, while also assessing demographic, clinical, and etiological factors. The goal is to establish the relevance of PSVD in the Indian population and the utility of invasive diagnostic tests.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic accuracy and treatment strategies for patients with portal hypertension and related conditions.

How similar studies have gone: While the approach of re-evaluating diagnostic criteria is not novel, the specific focus on the Indian population and the application of the VALDIG classification is relatively untested.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Patients of 12-70 years, either gender with clinical, pathological radiological diagnosis of NCPH

Exclusion Criteria:

* Any patients having Cirrhosis based on clinical, pathological, or radiological diagnosis
* Any patients having active malignancy

Where it's running

  • Dr. Madhumita Premkumar
    Sector-12, Chandigarh, India     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Portal Hypertension 45Non-Cirrhotic Portal Hypertension 4Post Graduate Institute of Medical Education and Research, Chandigarh 22
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.