Understanding Patient Preferences for PARP Inhibitors in Ovarian Cancer
Official title: Patient Preferences for Precision Medicine
Run by University of Saskatchewan · NCT06751303 · Data updated 2026-11-12
This study is trying to understand what women with ovarian cancer think about using a specific type of medication called PARP inhibitors to help them after chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | University of Saskatchewan Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Saskatoon, S) |
| Status | Recruiting |
| Started | September 17, 2023 |
| Main results expected | September 16, 2026 |
| Study ends | September 16, 2027 |
| Registry record updated | December 27, 2024 |
| Trial ID | NCT06751303 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with known or suspected stage 3/4 high grade serous or endometrioid ovarian cancer who can provide consent and complete questionnaires in English.
✕Probably not a fit
Patients who are ineligible for maintenance PARPi therapy or refuse HRD testing may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on patients with ovarian cancer who have defective DNA repair mechanisms and examines their preferences for maintenance therapy using PARP inhibitors (PARPi). It involves performing HRD testing to personalize treatment options based on the patients' responses to platinum-based chemotherapy. The study aims to evaluate treatment outcomes and quality of life in a real-world setting, providing insights into the efficacy and cost-effectiveness of PARPi therapy, particularly niraparib. By utilizing decision aids, the study seeks to empower patients in their treatment choices.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment options for ovarian cancer patients, improving their quality of life.
How similar studies have gone: Other studies have shown promise in using HRD testing to guide PARPi therapy, indicating that this approach has potential based on previous findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Known or suspected stage 3/4 high grade serous or endometrioid ovarian cancer Able to provide oral consent and complete questionnaires in English as per study protocol Exclusion Criteria: * Ineligible for Maintenace PARPi therapy Refusal to undergo HRD testing
Where it's running
-
Saskatchewan Cancer Center
Saskatoon, S, Canada Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.