Clinical trial Recruiting at 1 site Interventional Women only

Understanding Patient Preferences for PARP Inhibitors in Ovarian Cancer

Official title: Patient Preferences for Precision Medicine

Run by University of Saskatchewan · NCT06751303 · Data updated 2026-11-12

This study is trying to understand what women with ovarian cancer think about using a specific type of medication called PARP inhibitors to help them after chemotherapy.

More Ovarian Cancer trials

Quick facts

Study typeInterventional
SexWomen only
Enrollment100 (estimated)
SponsorUniversity of Saskatchewan
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Saskatoon, S)
StatusRecruiting
StartedSeptember 17, 2023
Main results expectedSeptember 16, 2026
Study endsSeptember 16, 2027
Registry record updatedDecember 27, 2024
Trial IDNCT06751303 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with known or suspected stage 3/4 high grade serous or endometrioid ovarian cancer who can provide consent and complete questionnaires in English.

Probably not a fit

Patients who are ineligible for maintenance PARPi therapy or refuse HRD testing may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients with ovarian cancer who have defective DNA repair mechanisms and examines their preferences for maintenance therapy using PARP inhibitors (PARPi). It involves performing HRD testing to personalize treatment options based on the patients' responses to platinum-based chemotherapy. The study aims to evaluate treatment outcomes and quality of life in a real-world setting, providing insights into the efficacy and cost-effectiveness of PARPi therapy, particularly niraparib. By utilizing decision aids, the study seeks to empower patients in their treatment choices.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment options for ovarian cancer patients, improving their quality of life.

How similar studies have gone: Other studies have shown promise in using HRD testing to guide PARPi therapy, indicating that this approach has potential based on previous findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Known or suspected stage 3/4 high grade serous or endometrioid ovarian cancer Able to provide oral consent and complete questionnaires in English as per study protocol

Exclusion Criteria:

* Ineligible for Maintenace PARPi therapy Refusal to undergo HRD testing

Where it's running

  • Saskatchewan Cancer Center
    Saskatoon, S, Canada
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.