Understanding patient preferences for colorectal cancer screening options
Understanding Patient Preference on Colorectal Cancer Screening Options
This study is trying to understand what people aged 45-75 who are at average risk for colorectal cancer think about different screening options, especially a new blood test, to see if it can encourage more people to get screened.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 45 Years to 75 Years |
| Sex | All |
| Sponsor | Milton S. Hershey Medical Center Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT05536713 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore patient preferences regarding different colorectal cancer screening methods, particularly focusing on the acceptance of a blood-based screening test. The study targets individuals aged 45-75 who are at average risk for colorectal cancer and have previously declined other screening options. By assessing patient attitudes and experiences, the research seeks to identify barriers to screening and enhance compliance with colorectal cancer detection methods. The blood-based test is designed to be non-invasive and convenient, potentially increasing participation rates in screening programs.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 45-75 at average risk for colorectal cancer who have previously refused or failed to complete a screening test.
Not a fit: Patients with a personal or family history of colorectal cancer or related syndromes may not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could lead to improved colorectal cancer screening rates and earlier detection, ultimately reducing mortality associated with the disease.
How similar studies have performed: Other studies have shown success with blood-based screening tests for colorectal cancer, indicating a promising approach to increasing screening compliance.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between 45-75 years of age * Have an average risk for colorectal cancer * A patient at one of our partner FQHCs * Received a screening order (either using a stool-based test or colonoscopy) six months ago and failed or refused to complete the screening test * Able to comprehend and willing to give informed consent * Able and willing to provide a blood sample per protocol Exclusion Criteria: 1. Family history * One first-degree relative diagnosed with CRC or advanced adenoma at age \< 60 years * Two first-degree relatives diagnosed with CRC or advanced adenoma at any age * Known hereditary gastrointestinal cancer syndromes, such as Lynch Syndrome or Familial Adenomatous and Polyposis (FAP) 2. Personal History * History of CRC or adenoma * History of cancers * History of inflammatory bowel disease, including chronic ulcerative colitis and Crohn's disease * Have a recorded up-to-date CRC screening * Blood product transfusion in the past 120 days * A medical condition that, in the opinion of the patient's health provider, should preclude enrollment in the study
Where this trial is running
Chicago, Illinois
- PCC Community Wellness Center — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Karen Kim, MD — University of Chicago
- Study coordinator: Helen Y Lam, Ph.D.
- Email: hvallina@medicine.bsd.uchicago.edu
- Phone: 773-702-2613
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.