Understanding Parent-Child Communication About Cancer Risk in Young People

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on children, adolescents, and young adults (CAYA) aged 10-24 years who have undergone genetic testing for cancer predisposition. It aims to explore how parents communicate with their CAYA about the implications of their genetic test results and the associated psychosocial outcomes. By utilizing questionnaires, behavioral observations, and qualitative interviews, the study seeks to identify barriers and facilitators in these communications. The findings will inform future genetic education strategies to enhance understanding and management of cancer risk.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient aged 10 to 24 years (inclusive)
* Patient underwent germline genetic testing with a Pathogenic/Likely Pathogenic (P/LP) variant in a known cancer predisposition gene that increases risk for developing cancer
* P/LP result disclosed to the patient
* Patient has a primary caregiver willing to participate
* Patient and participating caregiver able to speak and read English

Exclusion Criteria:

* Patient is only a carrier of a recessive variant that does not alone increase risk for cancer
* Inability or unwillingness of patient or participating caregiver or to give informed consent/assent
* Participating caregiver is under the age of 18 years
* Patient or participating caregiver has evidence of significant cognitive deficits (per medical record) that would interfere with the ability to comprehend study questions
* Patient's medical status or condition precludes completion of study (as determined by medical team, patient, or parent)

Where it's running

• St. Jude Children's Research Hospital
  Memphis, Tennessee, United States Recruiting

Study contacts

• Principal investigator: Katianne Sharp, PhD — St. Jude Children's Research Hospital
• Study coordinator: Katianne Sharp, PhD
• Email: referralinfo@stjude.org
• Phone: 888-226-4343

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.