Understanding osteoporosis caused by glucocorticoids in patients with chronic inflammatory diseases or psoriasis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to systematically collect and analyze data related to glucocorticoid-induced osteoporosis (GIOP) in patients suffering from chronic inflammatory rheumatic diseases or psoriasis. By gathering clinical, laboratory, and instrumental examination results from over 1000 patients, the research seeks to build a comprehensive GIOP databank. The study will also involve diagnostics and follow-up care for GIOP according to current guidelines, addressing the urgent need for more robust data on this adverse effect of glucocorticoid therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Every patient has to fulfill the following inclusion criteria:

* patients with (control group: without) a diagnosis of a chronic inflammatory rheumatic disease or psoriasis
* patients who (not for control groups) have/had already a glucocorticoid therapy, or patients in which the implementation of a new long-term GC therapy is expected
* patients who, according to the Dachverband Osteologie (DVO, Germany) guidelines, attend our osteoporosis and bone metabolism outpatient consultation hours or are referred by the hospital wards of the Charité for diagnosis, treatment or follow-up
* capability to understand the patient information
* consent to participation in the project and storage of data

Exclusion Criteria:

If any of the following exclusion criteria is true, the patient must not be included in this study:

* alcohol, medication and/or drug addiction
* severe psychiatric diseases limiting the comprehension of the project plan and the study protocol (persons incapable of giving informed consent)
* pregnant and lactating patients
* patients incapable of giving informed consent for any reason
* prisoners and all persons who are committed to an institution due to an official or judicial order

Where it's running

• Charité University Medicine Berlin (CCM)
  Berlin, State of Berlin, Germany Recruiting

Study contacts

• Principal investigator: Frank Buttgereit, Prof Dr — Charité University Medicine Berlin (CCM)
• Study coordinator: Frank Buttgereit, Prof Dr
• Email: frank.buttgereit@charite.de
• Phone: +49 30 450 513125

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.