Understanding Nonalcoholic Steatohepatitis in Chinese Children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate nonalcoholic steatohepatitis (NASH) in children, focusing on the histopathological features of pediatric nonalcoholic fatty liver disease (NAFLD). By analyzing biopsies and clinical data, the study seeks to document the prevalence and significance of various histological patterns in children, which may differ from those observed in adults. The goal is to better understand the natural history of NAFLD in the pediatric population and its potential implications for health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age 1-18 with biopsy-proven NAFLD
* Alcohol consumption less than 20g/day and 10g/day for boys and girls respectively

Exclusion Criteria:

* with viral hepatitis, e.g. HBV, HCV
* with a1-anti-trypsin disease
* with autoimmune hepatitis
* with Wilson disease
* with liver impaired by drugs

Where it's running

• Children's Liver Disease Center, 302 Hospital
  Beijing, China Recruiting

Study contacts

• Principal investigator: George Lau, MD, PhD — Humanity and Health Medical Centre
• Study coordinator: George Lau, MD, PhD
• Email: gkklau@hnhmgl.com
• Phone: 852-28613777

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.