Understanding new-onset atrial fibrillation in patients with heart attacks

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to validate the prognostic significance of new-onset atrial fibrillation (NOAF) in patients who have experienced an acute myocardial infarction (AMI). It will establish a multicenter, prospective registry involving patients from nine tertiary medical centers in China. The study will collect comprehensive data on patient demographics, cardiovascular risk factors, and NOAF characteristics, including its burden and patterns. Patients will be monitored for at least two years post-discharge to assess cardiovascular outcomes and the potential role of NOAF burden in guiding anticoagulation therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (\>18 years old);
* Patient with AMI (including STEMI and NSTEMI) who developed NOAF during the index hospitalization;
* Patients must have received in-hospital CEM for at least 5 days;
* Patients must give informed consent.

Exclusion Criteria:

* Patients with a medical history of pre-existing AF;
* Patients with a medical history of rheumatic valvular disease;
* Patients with a medical history of sick sinus syndrome;
* Patients undergoing emergent coronary artery bypass surgery;
* Patients who suffer malignant tumors with an expected lifetime less than 1 year ;
* Patients who refuse to receive CEM during hospitalization and the data of heart rhythm cannot be retrieved;
* Patients who refuse to receive percutaneous coronary intervention (PCI) or have contraindications for PCI;
* Patients who have died during the index hospitalization.

Where it's running

• Kaifeng Central Hospital
  Kaifeng, Henan, China Recruiting
• Luoyang Central Hospital
  Luoyang, Henan, China Recruiting
• The First Affiliated Hospital of Zhengzhou University
  Zhengzhou, Henan, China Recruiting
• Department of Cardiology, Shanghai Tenth People's Hospital
  Shanghai, Shanghai Municipality, China Recruiting
• Shanghai Seventh People's Hospital
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Yidong Wei, M.D., Ph.D. — Department of Cardiology, Shanghai Tenth People's Hospital
• Study coordinator: Jiachen Luo, M.D., Ph.D.
• Email: messichen@tongji.edu.cn
• Phone: +86-188-0179-0469

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.