Understanding muscle loss in patients with chronic lung diseases

Epidemiological Study of Sarcopenia in Patients With Chronic Lung Diseases: A Prospective Registry Cohort Study

Observational Taichung Veterans General Hospital · NCT06280443

This study looks at how muscle loss affects people with chronic lung diseases like COPD and ILD to see how common it is and how it relates to their overall health.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages20 Years and up
SexAll
SponsorTaichung Veterans General Hospital Academic / other
Locations1 site (Taichung)
Trial IDNCT06280443 on ClinicalTrials.gov

What this trial studies

This observational study focuses on outpatients diagnosed with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD) at Taichung Veterans General Hospital. Participants will undergo a series of assessments including the SARC-Calf questionnaire, grip strength tests, and various physical performance tests to evaluate the prevalence of sarcopenia. The study aims to analyze body composition using bioelectrical impedance analysis and dual-energy X-ray absorptiometry. Data collected will help explore the continuity of care and medical resource utilization among these patients.

Who should consider this trial

Good fit: Ideal candidates are outpatients aged 20 and older with COPD or ILD who do not require hospitalization.

Not a fit: Patients who are bedridden, unable to walk, or have terminal illnesses may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of muscle loss in chronic lung disease patients, potentially leading to better management strategies.

How similar studies have performed: Other studies have shown success in assessing sarcopenia in chronic diseases, indicating that this approach is supported by existing research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Outpatients with COPD (chronic obstructive pulmonary disease) or ILD (interstitial lung disease) from department of Chest medicine in Taichung Veterans General Hospital, judged by the doctor that they do not need hospitalization or emergent treatment.
2. Those who meet the conditions for frailty diagnosis after assessment by the Frailty Scale
3. Patients who agree to provide the ID card number to the research team for usage as a link to the National Health Insurance research database and Health bank to explore the continuity of care and the use of medical resources
4. Age\>=20

Exclusion Criteria:

1. Patients who refuse to sign the consent form
2. Patients who are bed ridden or unable to walk due to physical disabilities
3. Patients with terminal cancer or human acquired immunodeficiency syndrome
4. Patients with edema (pitting edema +2)

Where this trial is running

Taichung

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SarcopeniaCOPDAsthmaILD
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.