Understanding mood changes during pregnancy and after birth
Official title: Perinatal Thymic Dysregulation: Characterization of Perinatal Mood Episodes
Run by Centre Hospitalier Charles Perrens, Bordeaux · NCT07008183 · Data updated 2026-11-12
This project will see if using brief self-questionnaires during routine psychiatric visits helps standardize diagnosis and detect depressive, hypomanic, or mixed mood episodes in pregnant women and those up to one year after giving birth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | Centre Hospitalier Charles Perrens, Bordeaux Government |
| Locations | 1 site (Bordeaux, New Aquitaine) |
| Status | Recruiting |
| Started | October 13, 2025 |
| Main results expected | July 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | December 1, 2025 |
| Trial ID | NCT07008183 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18 or older who are pregnant or within one year postpartum presenting for their first psychiatric consultation about the current pregnancy, fluent in French, and affiliated with the French social security system.
✕Probably not a fit
Women already under psychiatric care, under court protection, or more than one year postpartum are not eligible and unlikely to receive benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional program integrates standardized self-report questionnaires into routine first psychiatric consultations for women who are pregnant or within 12 months postpartum. It aims to capture a broad range of perinatal mood presentations, including depressive, hypomanic, manic, and mixed features that are often under-recognized. The protocol records clinical criteria and contextual factors to better characterize episode patterns and guide therapeutic management. Participation requires French fluency, social security affiliation, and informed consent.
Why it matters
Potential benefit: If successful, this approach could enable earlier and more accurate recognition of perinatal hypomanic and mixed episodes, leading to improved treatment decisions and outcomes.
How similar studies have gone: Prior research has mainly targeted perinatal depression, and systematic capture of hypomanic and mixed symptoms in routine care remains relatively novel with limited prior evidence of effectiveness.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women over 18 years old * Pregnant or having given birth less than a year ago * First psychiatric consultation for the pregnancy concerned. * Good command of the French language. * Participant affiliated to the social security system * Participant who has given her consent to take part in the study. Exclusion Criteria: * Women who gave birth more than a year ago. * Participant under psychiatric care * Participant under court protection
Where it's running
-
Centre Hospitalier CHARLES PERRENS
Bordeaux, New Aquitaine, France Recruiting
Study contacts
- Principal investigator: Anne-Laure SUTTER-DALLAY, Prof Md PhD — Centre Hospitalier Charles Perrens
- Study coordinator: Anne-Laure SUTTER DALLAY, Prof, MD, PhD
- Email: alsutter@ch-perrens.fr
- Phone: +33 556561782
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.