Understanding mood changes during pregnancy and after birth
Perinatal Thymic Dysregulation: Characterization of Perinatal Mood Episodes
This project will see if using brief self-questionnaires during routine psychiatric visits helps standardize diagnosis and detect depressive, hypomanic, or mixed mood episodes in pregnant women and those up to one year after giving birth.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Centre Hospitalier Charles Perrens, Bordeaux Government |
| Locations | 1 site (Bordeaux, New Aquitaine) |
| Trial ID | NCT07008183 on ClinicalTrials.gov |
What this trial studies
This interventional program integrates standardized self-report questionnaires into routine first psychiatric consultations for women who are pregnant or within 12 months postpartum. It aims to capture a broad range of perinatal mood presentations, including depressive, hypomanic, manic, and mixed features that are often under-recognized. The protocol records clinical criteria and contextual factors to better characterize episode patterns and guide therapeutic management. Participation requires French fluency, social security affiliation, and informed consent.
Who should consider this trial
Good fit: Women aged 18 or older who are pregnant or within one year postpartum presenting for their first psychiatric consultation about the current pregnancy, fluent in French, and affiliated with the French social security system.
Not a fit: Women already under psychiatric care, under court protection, or more than one year postpartum are not eligible and unlikely to receive benefit from this protocol.
Why it matters
Potential benefit: If successful, this approach could enable earlier and more accurate recognition of perinatal hypomanic and mixed episodes, leading to improved treatment decisions and outcomes.
How similar studies have performed: Prior research has mainly targeted perinatal depression, and systematic capture of hypomanic and mixed symptoms in routine care remains relatively novel with limited prior evidence of effectiveness.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women over 18 years old * Pregnant or having given birth less than a year ago * First psychiatric consultation for the pregnancy concerned. * Good command of the French language. * Participant affiliated to the social security system * Participant who has given her consent to take part in the study. Exclusion Criteria: * Women who gave birth more than a year ago. * Participant under psychiatric care * Participant under court protection
Where this trial is running
Bordeaux, New Aquitaine
- Centre Hospitalier CHARLES PERRENS — Bordeaux, New Aquitaine, France (Recruiting)
Study contacts
- Principal investigator: Anne-Laure SUTTER-DALLAY, Prof Md PhD — Centre Hospitalier Charles Perrens
- Study coordinator: Anne-Laure SUTTER DALLAY, Prof, MD, PhD
- Email: alsutter@ch-perrens.fr
- Phone: +33 556561782
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.