Improving mental health support for pregnant and postpartum individuals

Collaborative Care Model for Perinatal Depression Support Services -- Population-Level Equity-Centered Systems Change (COMPASS-PLUS): A Hybrid Type 2 Cluster Randomized Trial

Not applicable Interventional Women and Infants Hospital of Rhode Island · NCT06849869

This study is testing a new approach to mental health support for pregnant and new moms to see if it can help reduce feelings of depression and thoughts of self-harm.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment14820 (estimated)
Ages18 Years and up
SexFemale
SponsorWomen and Infants Hospital of Rhode Island Academic / other
Locations1 site (Providence, Rhode Island)
Trial IDNCT06849869 on ClinicalTrials.gov

What this trial studies

This study aims to adapt the collaborative care model (CCM) to enhance perinatal mental health services, focusing on integrating mental health care into primary care settings. The intervention, known as COMPASS+, will be evaluated for its effectiveness in reducing depression symptoms and suicidal ideation among pregnant and postpartum individuals. The study will also assess the implementation of COMPASS+ using the RE-AIM framework to ensure it meets the unique needs of perinatal care. By addressing social determinants of mental health and promoting health equity, this approach seeks to improve outcomes for a population that often faces significant disparities in care.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant and postpartum individuals aged 18 and older receiving care at participating sites.

Not a fit: Patients under 18 years of age will not be eligible for this study and therefore may not receive its benefits.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce depression and improve mental health outcomes for pregnant and postpartum individuals.

How similar studies have performed: Previous studies have shown the effectiveness of the collaborative care model in improving depression outcomes, but its application in perinatal care is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all pregnant and postpartum people receiving care at participating sites, who reach a gestational age of 20 or more weeks
* age \> 17 years

Exclusion Criteria:

* age \< 18 years
* all pregnant and postpartum people receiving care at participating sites, who do not reach a gestational age of 20 or more weeks

Where this trial is running

Providence, Rhode Island

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Perinatal Mental Healthhealth services interventionsmental healthcollaborative care modelcompass+perinatal care
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.