Understanding moderate to severe tricuspid regurgitation and its outcomes
Clinical and Echocardiographic Characteristics and Prognosis of trIcuspid regurgiTation (EPIT): Prospective and Retrospective Follow-up of a Cohort of Patients With Moderate or Severe Tricuspid Regurgitation
Centre Hospitalier Universitaire, Amiens · NCT03546231
This study looks at patients with moderate to severe tricuspid regurgitation to see how it affects their heart health and when surgery might be needed.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Months and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens (other) |
| Locations | 1 site (Amiens) |
| Trial ID | NCT03546231 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the characteristics and prognosis of patients with moderate or severe tricuspid regurgitation (TR). The tricuspid valve, often overlooked in echocardiography, plays a crucial role in heart function, and TR can lead to significant complications, including right heart failure. The study aims to better define the timing for surgical intervention in patients with TR, as current guidelines are vague due to a lack of prognostic data. By utilizing transthoracic echocardiography, the study will assess the hemodynamic impact of TR and its progression over time.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with moderate or severe tricuspid regurgitation.
Not a fit: Patients who have previously undergone surgery for the tricuspid valve or refuse to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies and surgical timing for patients with tricuspid regurgitation, potentially enhancing patient outcomes.
How similar studies have performed: While there is limited data on tricuspid regurgitation management, this study addresses a poorly codified area, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 ans * inclusion criteria: moderate or severe tricuspid regurgitation * exclusion criteria: Refusal to participate/ prior surgery of the tricuspid valve
Where this trial is running
Amiens
- CHU Amiens-Picardie — Amiens, France (RECRUITING)
Study contacts
- Principal investigator: Christophe TRIBOUILLOY, Pr — CHU AMIENS-PICARDIE
- Study coordinator: Christophe TRIBOUILLOY, Pr
- Email: Tribouilloy.Christophe@chu-amiens.fr
- Phone: 03 22 45 58 85
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Tricuspid Valve Disease, Tricuspid regurgitation, tricuspid valve, surgery, outcome, prognosis, mortality, right ventricle