Understanding long-term effects of Type 1 Diabetes in patients
Clinical Characteristics of People With Long-term Type 1 Diabetes: a Cohort Study
This study is trying to learn more about the long-term effects of Type 1 Diabetes in people who have had it for at least 10 years, by looking at their health data over three years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Sex | All |
| Sponsor | Second Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Trial ID | NCT05359796 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect clinical and laboratory data from 400 patients with Type 1 Diabetes (T1D) who have had the condition for at least 10 years. Over a period of three years, patients will be followed up annually to explore risk and protective factors associated with microvascular complications. The study will utilize regression analysis to identify these factors and ensure data accuracy through a dual-entry system for data collection. The findings aim to enhance understanding of long-term T1D characteristics, particularly in the context of the Chinese population.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with Type 1 Diabetes for 10 years or more who are insulin-dependent.
Not a fit: Patients with Type 2 diabetes, gestational diabetes, or other specific types of diabetes will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prediction and prevention strategies for microvascular complications in long-term T1D patients.
How similar studies have performed: While studies on long-term T1D exist, this specific focus on the Chinese population and the identification of protective factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals diagnosed with type 1 diabetes(T1D) according to the 1999 World Health Organization report * Insulin dependence from disease onset * with T1D duration of ≥10 years * able to understand the procedures and methods of this study, voluntarily participate in the study, and agree to sign the informed consent form Exclusion Criteria: * patients with type 2 diabetes, gestational diabetes, or specific types of diabetes * patients with mental disability or have any other condition or disease that may hamper compliance with the protocol
Where this trial is running
Changsha, Hunan
- Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University — Changsha, Hunan, China (Recruiting)
Study contacts
- Principal investigator: Xia Li, MD/PHD — Central South University
- Study coordinator: Xia Li, MD/PHD
- Email: lixia2014@vip.163.com
- Phone: +86 17373199692
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.