Understanding knee osteoarthritis in relation to aging and metabolic syndrome

What Affects the Severity of Knee Osteoarthritis? Aging or Associated Metabolic Syndrome

Observational Sohag University · NCT05955573

This study looks at how aging and metabolic syndrome affect knee osteoarthritis in patients to better understand their relationship.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages30 Years and up
SexAll
SponsorSohag University Academic / other
Locations1 site (Sohag)
Trial IDNCT05955573 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the relationship between knee osteoarthritis (OA), aging, and metabolic syndrome. Conducted at Sohag University Hospital, it will involve a cross-sectional analysis of patients who meet the American College of Rheumatology criteria for knee OA. Data collected will include demographic information, anthropometric measures, clinical symptoms, and laboratory findings. The study will utilize plain radiographs to assess the severity of OA in participants.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals who meet the ACR criteria for knee osteoarthritis and have symptomatic OA in at least one knee.

Not a fit: Patients with a history of knee trauma or other forms of arthritis may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of knee osteoarthritis and its links to aging and metabolic syndrome, potentially leading to improved management strategies.

How similar studies have performed: While there have been studies on knee osteoarthritis, this specific focus on aging and metabolic syndrome is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who met the American College of Rheumatology (ACR) clinical criteria for knee OA and had symptomatic OA of at least 1 knee (index knee), with a Kellgren / Lawrence (K/L) score ≥ 1 in that knee

Exclusion Criteria:

* Any patient with a history of trauma to the knee

  * Any other form of arthritis (e.g., rheumatoid arthritis, seronegative spondyloarthropathies, gout, pyrophosphate disease, or other crystal arthropathy)

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knee Osteoarthritisknee osteoarthritisAgingMetabolic Syndrome
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.