Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding ileorectal syndrome after total colectomy

Official title: Trying to Define Ileorectal Syndrome: a Prospective Observational Study

Run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital · NCT07385196 · Data updated 2026-11-12

This project will follow adults who had a total colectomy with ileorectal anastomosis to see how common and how severe ileorectal syndrome is and how it affects quality of life.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorSaglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Academic / other
Locations1 site (Diyarbakır)
StatusRecruiting
StartedDecember 19, 2025
Main results expectedDecember 19, 2026
Study endsFebruary 15, 2027
Registry record updatedFebruary 3, 2026
Trial IDNCT07385196 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age ≥18) who have undergone ileorectal anastomosis or have a preserved rectum after colorectal surgery and who can give informed consent and complete follow-up surveys are ideal candidates.

Probably not a fit

People with a permanent stoma, who have had total rectal excision, or who cannot complete follow-up visits or questionnaires are unlikely to benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational survey of adults with an ileorectal anastomosis or preserved rectum after colorectal surgery, using serial questionnaires and clinical data to document bowel symptoms and quality of life. The primary focus is measuring the frequency, symptom severity, and quality-of-life impact of ileorectal syndrome. Secondary analyses will explore relationships between specific postoperative bowel dysfunctions and quality of life and identify clinical factors associated with worse symptoms. Participants will be recruited from the general surgery clinic at Gazi Yaşargil Training and Research Hospital and followed with planned prospective assessments.

Why it matters

Potential benefit: If successful, the findings could improve postoperative follow-up and symptom management for people after total colectomy by clarifying common problems and risk factors.

How similar studies have gone: Previous reports, mostly retrospective or small prospective series, have described postoperative bowel dysfunction but large prospective, systematic data on ileorectal syndrome are limited, so this study adds more structured prospective evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: Age ≥18 years

History of ileorectal anastomosis or preserved rectum following colorectal surgery

Ability to understand the study procedures and provide written informed consent

Willingness to participate in prospective follow-up assessments -

Exclusion Criteria:

Age \<18 years

Permanent stoma

Total rectal excision

Inability to complete follow-up assessments

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Where it's running

  • general surgery clinic(Gazi Yaşargil Tr and Res Hospital
    Diyarbakır, Turkey (Türkiye)
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.