Understanding ileorectal syndrome after total colectomy
Trying to Define Ileorectal Syndrome: a Prospective Observational Study
This project will follow adults who had a total colectomy with ileorectal anastomosis to see how common and how severe ileorectal syndrome is and how it affects quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Academic / other |
| Locations | 1 site (Diyarbakır) |
| Trial ID | NCT07385196 on ClinicalTrials.gov |
What this trial studies
This is a prospective observational survey of adults with an ileorectal anastomosis or preserved rectum after colorectal surgery, using serial questionnaires and clinical data to document bowel symptoms and quality of life. The primary focus is measuring the frequency, symptom severity, and quality-of-life impact of ileorectal syndrome. Secondary analyses will explore relationships between specific postoperative bowel dysfunctions and quality of life and identify clinical factors associated with worse symptoms. Participants will be recruited from the general surgery clinic at Gazi Yaşargil Training and Research Hospital and followed with planned prospective assessments.
Who should consider this trial
Good fit: Adults (age ≥18) who have undergone ileorectal anastomosis or have a preserved rectum after colorectal surgery and who can give informed consent and complete follow-up surveys are ideal candidates.
Not a fit: People with a permanent stoma, who have had total rectal excision, or who cannot complete follow-up visits or questionnaires are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, the findings could improve postoperative follow-up and symptom management for people after total colectomy by clarifying common problems and risk factors.
How similar studies have performed: Previous reports, mostly retrospective or small prospective series, have described postoperative bowel dysfunction but large prospective, systematic data on ileorectal syndrome are limited, so this study adds more structured prospective evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Age ≥18 years History of ileorectal anastomosis or preserved rectum following colorectal surgery Ability to understand the study procedures and provide written informed consent Willingness to participate in prospective follow-up assessments - Exclusion Criteria: Age \<18 years Permanent stoma Total rectal excision Inability to complete follow-up assessments \-
Where this trial is running
Diyarbakır
- general surgery clinic(Gazi Yaşargil Tr and Res Hospital — Diyarbakır, Turkey (Türkiye) (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.