Understanding how tuberculosis affects the placenta during pregnancy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the impact of tuberculosis (TB) infection on the development and function of the placenta in pregnant women. It will enroll women attending delivery clinics in Addis Abeba, Ethiopia, and classify them based on TB infection using a blood test. The study will compare outcomes such as pathological lesions of the placenta, gene and protein expression patterns, and infant outcomes at birth and six weeks after birth between women with and without TB infection. The goal is to uncover potential pregnancy-related disorders linked to TB infection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women admitted for delivery to study sites
* Written informed consent
* Age 18 years or greater

Exclusion Criteria:

* Chronic comorbidities (other than TB, HIV or pregnancy-related disorder)
* Twin pregnancy

Where it's running

• Gandhi Memorial Hospital
  Addis Ababa, Ethiopia Recruiting

Study contacts

• Principal investigator: Per Bjorkman, MD, PhD — Lund University
• Study coordinator: Per Bjorkman, MD, PhD
• Email: per.bjorkman@med.lu.se
• Phone: +46-40337711

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.