Understanding how the brain's posterior cingulate cortex affects memory decisions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates the role of the posterior cingulate cortex (PCC) in episodic memory by utilizing intracranial recordings and stimulation during routine clinical monitoring of brain activity in epilepsy patients. The study aims to differentiate how various subregions of the PCC contribute to memory-based decision-making processes. By focusing on the executive functions associated with memory retrieval, the research seeks to uncover the neural mechanisms that support the integration and evaluation of past experiences. The findings could enhance our understanding of memory behavior and its underlying brain functions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All participants are patients undergoing invasive brain monitoring for epilepsy and will be asked to consent to participation in this basic science protocol (which is focused on the patient group but is not focused on the study of epilepsy).

Exclusion Criteria:

* Individuals not undergoing invasive brain monitoring for epilepsy.
* Individuals outside of the age range (18-50 yrs).
* Individuals with cognitive impairment or intellectual difficulty.

Where it's running

• Hospital of the University of Pennsylvania - Pavilion
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Ilaina Edelstein
• Email: Ilaina.Edelstein@Pennmedicine.upenn.edu
• Phone: 2156153525

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.