Understanding how stress and diet affect obesity in adolescents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop personalized dietary interventions for adolescents aged 11 to 17 who are overweight or obese by examining the relationship between emotional stress, gut microbiome functionality, and dietary patterns. Participants will provide saliva, stool, and hair samples, along with completing questionnaires about their mental and medical health. The study will utilize metabolomics to analyze these samples and identify biomarkers associated with obesity and stress. The goal is to determine if personalized dietary approaches are more effective than general dietary recommendations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 11-17 years

Exclusion Criteria:

* Obesity/overweight
* Type 1 diabetes
* Medical conditions including pancreatic failure
* Developmental and hormonal disorders. E.g. thyroid problems, adrenal problems, Kallmann's syndrome, Klinefelter's syndrome, Prader-Willi syndrome (PWS), Congenital hypogonadotropic hypogonadism (CHH), ...
* Pregnancy
* In treatment with systemic concentrations of corticosteroids (cortisone). Eg cortisone/betamethasone/Dexamethasone/Fludrocortisone/Hydrocortisone in pill form or administration by injections.

Where it's running

• AZ Jan Palfijn Gent, Oost-Vlaanderen, Belgium, 9000
  Ghent, Oost-Vlaanderen, Belgium Recruiting
• Ghent University Hospital
  Ghent, Oost-Vlaanderen, Belgium Recruiting
• Clairs Vallons
  Ottignies-Louvain-la-Neuve, Waals Brabant, Belgium Recruiting
• Zeepreventorium
  De Haan, West-Vlaanderen, Belgium Recruiting
• AZ Delta
  Roeselare, West-Vlaanderen, Belgium Recruiting
• UZ Antwerpen
  Antwerp, Belgium Recruiting

Study contacts

• Principal investigator: Stefaan de Henauw, Prof — University Hospital, Ghent
• Study coordinator: Emile Callemeyn, Dr
• Email: emile.callemeyn@ugent.be
• Phone: +32473271636

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Nudge-Based Exercise for Obese Adolescents

  A nudge-based exercise program is being tested to see if it helps overweight teens start and keep up physical activity and improve BMI.

  Recruiting Nanjing Children's Hospital · Nanjing, Jiangsu · NCT07824453

• Tongue ultrasound for children and teens with obesity

  For children and teens with obesity enrolled in a 30-week inpatient weight-loss program, this project uses ultrasound to see if tongue size, fat content, and stiffness relate to body measurements and sleep apnea and change after the program.

  Recruiting Haute Ecole Bruxelles-Brabant · Brussels and 1 other locations · NCT07370350

• Outcomes for children with obesity in the Get Up & Go healthy lifestyle program

  This project will try whether the Get Up & Go family healthy lifestyle program helps children ages 6–14 with BMI at or above the 85th percentile improve health and activity measures compared with a waitlisted group.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT07342855

• Virtual Housecalls for teens: helping adolescents with obesity in primary care

  A telehealth-based program tests a 6-month intensive lifestyle approach to help adolescents aged 12-15 with class I obesity lose weight, using caregiver support and in-person visits plus virtual coaching.

  Recruiting Virginia Commonwealth University · Henrico, Virginia · NCT07246603

• How children's food and activity preferences and decision-making relate to weight over time

  This study will see if changes in how 9–14-year-old children value food and activity and how they make choices predict weight gain in children from low-income BIPOC and Hispanic families.

  Recruiting State University of New York at Buffalo · Buffalo, New York · NCT07229508

• School program to improve nutrition, physical activity, and school surroundings for Mexican 4th graders

  This project will test whether a school-centered program that changes food, activity, and social surroundings can improve weight and health measures in 9–12-year-old students in three Mexican states.

  Recruiting Mexican National Institute of Public Health · Cuernavaca, Morelos · NCT07185789

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.