Understanding how sensory memory affects speech learning
Role of Sensory Working Memory in Speech Motor Learning Aim 2
This study is testing how well people can learn to adapt their speech when their memory and brain activity are affected, to see if it helps improve their speech skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 21 Years to 40 Years |
| Sex | All |
| Sponsor | Yale University Academic / other |
| Locations | 1 site (Montréal, Quebec) |
| Trial ID | NCT04818268 on ClinicalTrials.gov |
What this trial studies
This study investigates the connection between sensory working memory and the ability to adapt speech motor skills. Participants will be divided into two groups, each undergoing auditory and somatosensory working memory tests followed by adaptation to altered auditory feedback. Additionally, continuous theta-burst transcranial magnetic stimulation (cTBS) will be applied to disrupt activity in a specific brain region to evaluate its role in speech motor adaptation. The study aims to quantify the effects of these interventions on working memory and speech adaptation.
Who should consider this trial
Good fit: Ideal candidates for this study are right-handed adults without any known physical or neurological abnormalities.
Not a fit: Patients with a history of neurological issues, certain medical implants, or those currently on specific psychiatric medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could enhance therapeutic approaches for individuals with speech motor disorders.
How similar studies have performed: While the approach of using cTBS in this context is relatively novel, similar studies have shown promise in understanding the neural mechanisms of learning and adaptation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * right handed adults * no known physical or neurological abnormalities Exclusion Criteria: * patients with: * cardiac pacemaker * surgical clips or values on the heart * implants * metal or metallic fragments in any part of the body * pregnancy * claustrophobia * a personal or family history of epilepsy * currently taking antipsychotic drugs * currently taking antidepressant drugs * currently taking antianxiety drugs * history of concussion.
Where this trial is running
Montréal, Quebec
- McGill University — Montréal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: David Ostry — Haskins Laboratories
- Study coordinator: David Ostry
- Email: david.ostry@yale.edu
- Phone: 2038656163
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.