Understanding how individual factors affect blood sugar levels after meals in people with Type 2 Diabetes
Exploring Individual Determinants of postpranDIAl Glucose Response in Type 2 diaBEteS to opTimize Therapeutic Strategies With a Personalized Approach (DIABEST)
This study looks at how different personal factors affect blood sugar levels after meals in people with Type 2 Diabetes to help create better eating and treatment plans.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 144 (estimated) |
| Ages | 30 Years to 70 Years |
| Sex | All |
| Sponsor | Federico II University Academic / other |
| Locations | 1 site (Naples) |
| Trial ID | NCT06057246 on ClinicalTrials.gov |
What this trial studies
This study investigates the postprandial glucose response (PGR) in individuals with Type 2 Diabetes by examining various personal determinants such as genetics, gut microbiota, and lifestyle habits. Participants will undergo a 7-day observational period, including continuous glucose monitoring and dietary tracking, to assess their glucose levels after consuming standardized meals. The goal is to identify patterns in glucose response that could inform personalized nutritional and therapeutic strategies for better diabetes management.
Who should consider this trial
Good fit: Ideal candidates include men and post-menopausal women with Type 2 Diabetes, an HbA1c level of 7.5% or lower, and a BMI between 20 and 39.9 kg/m2.
Not a fit: Patients with acute or chronic conditions that could affect study results, or those who are pregnant or breastfeeding, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized dietary recommendations that improve blood sugar control for patients with Type 2 Diabetes.
How similar studies have performed: Other studies have shown promise in using continuous glucose monitoring to personalize dietary strategies, indicating that this approach has potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and post-menopausal women * HbA1c ≤ 7.5% * Body Mass Index (BMI) 20-39.9 kg/m2 * Ability to comply with the study protocol activities. Exclusion Criteria: * Any acute or chronic condition possibly influencing the interpretation of the results or possibly worsened because of study participation * Pregnancy or breast-feeding * Use of antibiotics, probiotics, or prebiotics during the last three months.
Where this trial is running
Naples
- Department of Clinical Medicine and Surgery Federico II University — Naples, Italy (Recruiting)
Study contacts
- Study coordinator: Angela A Rivellese, Professor
- Email: rivelles@unina.it
- Phone: 00390817463665
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.