Understanding how chronic liver disease patients with organ failure fare after non‑emergency hospital stays
Official title: To Study the Clinical Course and Outcomes of Non-electively Hospitalised Patients of Chronic Liver Disease (CLD) With Hepatic or Extra-hepatic Predominant Organ Failure(s) at 6 Months.
Run by Institute of Liver and Biliary Sciences, India · NCT07270809 · Data updated 2026-11-12
This study follows adults with chronic liver disease who are admitted to the hospital non-electively to see how their condition develops over six months when liver and/or other organs fail.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Institute of Liver and Biliary Sciences, India Academic / other |
| Locations | 1 site (New Delhi, National Capital Territory of Delhi) |
| Status | Recruiting |
| Started | April 15, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | August 11, 2026 |
| Trial ID | NCT07270809 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–70 with chronic liver disease (with or without cirrhosis) who are non‑electively hospitalized for decompensation, regardless of prior decompensation history.
✕Probably not a fit
Patients with hepatocellular carcinoma, noncirrhotic portal hypertension conditions (NCPF/EHPVO), pregnancy, or prior liver transplant are not expected to benefit from this observational study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational study conducted at ILBS in New Delhi. It tracks adults with chronic liver disease who are non‑electively hospitalized, documenting their clinical course, organ failures, therapies, and outcomes over six months. The goal is to identify differences in progression and prognosis related to liver failure with or without extra‑hepatic organ failure. Laboratory, clinical, inflammatory, and regenerative markers are collected to explore potential disease trajectories. No intervention is provided as part of the study; data are used to understand real-world outcomes.
Why it matters
Potential benefit: Findings could help clinicians better predict outcomes and tailor care for patients with chronic liver disease and organ failure after hospitalization.
How similar studies have gone: Other observational cohorts have described outcomes in ACLF and decompensated liver disease, but this study aims to clarify regional differences in clinical course and organ failure patterns.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 18-70 years 2. CLD with or without cirrhosis with 1st or subsequent admissions for decompenasation and irrespective of any prior decompensation 3. Non-electively hospitalized Exclusion Criteria: 1. HCC 2. NCPF/EHPVO 3. Pregnancy 4. Post-Liver transplant
Where it's running
-
Institute of Liver & Biliary Sciences (ILBS)
New Delhi, National Capital Territory of Delhi, India Recruiting
Study contacts
- Study coordinator: Dr Amanjot Kaur, MD
- Email: amanjotbahri@gmail.com
- Phone: 01146300000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.