Understanding how cannabis affects mood and perception

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the effects of cannabis on mental and physical states, focusing on mood, cognition, perception of temperature and pain, and heart rate. Participants will engage in two in-person visits over the course of one week, completing various tasks that will take approximately 2.5 hours in total. The study will utilize water temperature variations as part of the experimental interventions to assess these effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 21-65 years of age
* Endorsement of at least some use of cannabis for coping purposes (\>1 on CMMQ)
* Regularly use flower cannabis products (i.e., ≥1x/week in the last 6 months)
* Proficient in English language
* At least occasional use of CBD+THC or CBD-dominant products (e.g., ≥1x/month)

Exclusion Criteria:

* Diagnosis or use of medications for substance use or psychotic disorders
* Report of other drug use (cocaine, opiates, methamphetamine) in the past 90 days or fail urine screen for any of these drugs
* Females cannot be pregnant or trying to become pregnant or nursing mothers
* Not able to provide informed consent

Where it's running

• University of Colorado at Boulder
  Boulder, Colorado, United States Recruiting

Study contacts

• Study coordinator: Carillon Skrzynski, PhD
• Email: carillon.skrzynski@colorado.edu
• Phone: (734)788-2961

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• vEAET-H: a virtual group emotional therapy for chronic pain patients using medical cannabis in Israel

  This study tests a Hebrew, virtual, group-based emotional therapy to see if it can help reduce pain and improve emotional well-being in Israeli adults with chronic musculoskeletal pain who use medical cannabis.

  Recruiting Reuth Rehabilitation Hospital · Tel Aviv · NCT07732062

• Testing warning labels on cannabis packaging to see what design helps people notice risks

  Researchers are testing different cannabis warning labels to see which designs make people notice health risks and think about their use more carefully.

  Recruiting University of Oklahoma · Oklahoma City, Oklahoma · NCT07701304

• Mobile app to help adults in Quebec use cannabis more safely

  A mobile app is being tested to see if it helps adults who use cannabis non-medically in Quebec use cannabis more safely.

  Recruiting Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec · NCT07524985

• Feasibility of a perinatal smoking and cannabis cessation program

  This study tests a perinatal program to help pregnant people quit tobacco and cannabis and stay smoke-free after birth.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07489443

• Psychiatric Symptoms in Methamphetamine Psychosis With or Without Lifetime Cannabis Use

  This study tests whether lifetime cannabis use changes the course and severity of psychiatric symptoms in people hospitalized with methamphetamine-induced psychosis.

  Recruiting Elazığ Mental Health and Diseases Hospital · Elâzığ, Elâzığ and 1 other locations · NCT07459270

• Cannabis use and IV sedation during wisdom tooth removal

  This project will see if people who use cannabis need different IV sedative doses or have different vital signs and breathing during wisdom tooth removal compared with people who don't use cannabis.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07423195

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.