Understanding how cannabis affects mood and perception
Exploring the Antecedents and Consequences of Cannabis Use in the Context of Coping: An Experimental Study
NA · University of Colorado, Boulder · NCT06588582
This study is testing how cannabis affects mood and how people feel things like temperature and pain in order to help understand its impact on mental and physical states.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 166 (estimated) |
| Ages | 21 Years to 65 Years |
| Sex | All |
| Sponsor | University of Colorado, Boulder (other) |
| Locations | 1 site (Boulder, Colorado) |
| Trial ID | NCT06588582 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the effects of cannabis on mental and physical states, focusing on mood, cognition, perception of temperature and pain, and heart rate. Participants will engage in two in-person visits over the course of one week, completing various tasks that will take approximately 2.5 hours in total. The study will utilize water temperature variations as part of the experimental interventions to assess these effects.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21-65 who regularly use cannabis for coping and have experience with both CBD and THC products.
Not a fit: Patients with substance use or psychotic disorders, or those who have recently used other illicit drugs, will not benefit from this study.
Why it matters
Potential benefit: If successful, this research could provide insights into how cannabis use influences emotional and sensory experiences, potentially guiding therapeutic applications.
How similar studies have performed: While there have been studies on cannabis effects, this specific focus on perceptual influences is relatively novel and less explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 21-65 years of age * Endorsement of at least some use of cannabis for coping purposes (\>1 on CMMQ) * Regularly use flower cannabis products (i.e., ≥1x/week in the last 6 months) * Proficient in English language * At least occasional use of CBD+THC or CBD-dominant products (e.g., ≥1x/month) Exclusion Criteria: * Diagnosis or use of medications for substance use or psychotic disorders * Report of other drug use (cocaine, opiates, methamphetamine) in the past 90 days or fail urine screen for any of these drugs * Females cannot be pregnant or trying to become pregnant or nursing mothers * Not able to provide informed consent
Where this trial is running
Boulder, Colorado
- University of Colorado at Boulder — Boulder, Colorado, United States (RECRUITING)
Study contacts
- Study coordinator: Carillon Skrzynski, PhD
- Email: carillon.skrzynski@colorado.edu
- Phone: (734)788-2961
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cannabis Use, Stress