Understanding how breast cancer spreads to the brain

Evaluation of Brain Metastasis Development Mechanism in Patients With Breast Cancer With Brain Metastasis(BCBM)

Not applicable Interventional Samsung Medical Center · NCT06330870

This study is trying to understand how breast cancer spreads to the brain in patients who have had surgery for brain tumors, to help find better treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
SexFemale
SponsorSamsung Medical Center Academic / other
Locations1 site (Seoul)
Trial IDNCT06330870 on ClinicalTrials.gov

What this trial studies

This study investigates the mechanisms behind the development of brain metastasis in patients diagnosed with breast cancer. It focuses on patients who have undergone curative surgery for brain metastasis and utilizes whole genome sequencing and tumor microenvironment evaluation as its primary interventions. The goal is to uncover biological factors that contribute to the spread of breast cancer to the brain, which could lead to improved treatment strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with breast cancer who have undergone curative surgery for brain metastasis.

Not a fit: Patients who have undergone Gamma Knife surgery will not benefit from this study.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for breast cancer patients with brain metastasis.

How similar studies have performed: While there may be studies exploring similar mechanisms, this specific approach focusing on breast cancer brain metastasis is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Breast cancer
* Brain metastasis curative surgery patient

Exclusion Criteria:

* Gamma Knife surgery patient

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast CancerBrain Metastasis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.