Clinical trial Recruiting at 1 site Interventional Women only

Understanding how breast cancer spreads to the brain

Official title: Evaluation of Brain Metastasis Development Mechanism in Patients With Breast Cancer With Brain Metastasis(BCBM)

Run by Samsung Medical Center · NCT06330870 · Data updated 2026-11-12

This study is trying to understand how breast cancer spreads to the brain in patients who have had surgery for brain tumors, to help find better treatments.

Quick facts

Study typeInterventional
SexWomen only
Enrollment30 (estimated)
SponsorSamsung Medical Center
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedApril 6, 2023
Main results expectedFebruary 5, 2025
Study endsDecember 31, 2027
Registry record updatedMarch 26, 2024
Trial IDNCT06330870 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with breast cancer who have undergone curative surgery for brain metastasis.

Probably not a fit

Patients who have undergone Gamma Knife surgery will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the mechanisms behind the development of brain metastasis in patients diagnosed with breast cancer. It focuses on patients who have undergone curative surgery for brain metastasis and utilizes whole genome sequencing and tumor microenvironment evaluation as its primary interventions. The goal is to uncover biological factors that contribute to the spread of breast cancer to the brain, which could lead to improved treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for breast cancer patients with brain metastasis.

How similar studies have gone: While there may be studies exploring similar mechanisms, this specific approach focusing on breast cancer brain metastasis is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Breast cancer
* Brain metastasis curative surgery patient

Exclusion Criteria:

* Gamma Knife surgery patient

Where it's running

  • Ji-Yeon Kim
    Seoul, South Korea
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.