Understanding how aging affects health and function
Arlington Study of Healthy Aging
The University of Texas at Arlington · NCT06857877
This study looks at how aging affects health and everyday abilities to help understand and improve ways to prevent and manage age-related issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 770 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | The University of Texas at Arlington (other) |
| Locations | 1 site (Arlington, Texas) |
| Trial ID | NCT06857877 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the mechanisms behind functional decline associated with aging by utilizing exercise science, neuroscience, and remote monitoring techniques. Participants will undergo a series of assessments including medical history, cognitive function tests, and physical performance evaluations over two visits. The study will also explore how personal, societal, racial, and sex factors influence aging and its related health outcomes. The findings could enhance our understanding of aging and inform strategies for disease prevention and management.
Who should consider this trial
Good fit: Ideal candidates include healthy men and women aged 50-80 years, as well as younger individuals aged 18-30 years for comparison purposes.
Not a fit: Patients with clinical diagnoses of dementia, major depression, or significant mobility impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing and managing age-related diseases and disabilities.
How similar studies have performed: Other studies have shown success in understanding aging through similar observational approaches, making this a promising area of research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Phase 1: Young healthy men and women between 18 - 30 years of age, and older men and women between 50 - 80 years of age. Phase 2: Men and women living in Tarrant County, Texas, between 50 - 85 years of age. In addition, the investigators will study up to 120 younger men and women, between 18-30 years of age, equally divided by race/ethnicity (same as above) and sex, to serve as reference controls. Exclusion Criteria: Phase 1: Clinical diagnosis of dementia; major depression (diagnosed by a physician), visual or auditory impairments that preclude neuropsychological testing or otherwise jeopardize the health and wellbeing of the participant during testing, non-ambulatory status (i.e. less than 10 m without mobility aid), shortness of breath while performing normal activities of daily living (walking through grocery store), body mass index greater than 45 kg/m2, heart failure or cardiomyopathy, acute coronary syndrome, primary valvular heart disease, severe gait disorder due to musculoskeletal disease or neurological motor deficit (e.g. severe osteoarthritis, lower limb amputation, Parkinson's disease, major stroke with motor sequelae); daily consumption of more than two alcoholic beverages; current treatment for cancer, and estimated life expectancy less than 4 years. Inclusion/exclusion will be verified using the demographics and medical history. Phase 2: Clinical diagnosis of dementia; major depression (diagnosed by a physician), visual or auditory impairments that preclude neuropsychological testing or otherwise jeopardize the health and wellbeing of the participant during testing, non-ambulatory status (i.e. less than 10 m without mobility aid), shortness of breath while performing normal activities of daily living (walking through grocery store), body mass index greater than 45 kg/m2, heart failure or cardiomyopathy, acute coronary syndrome, primary valvular heart disease, severe gait disorder due to musculoskeletal disease or neurological motor deficit (e.g. severe osteoarthritis, lower limb amputation, Parkinson's disease, major stroke with motor sequelae), daily consumption of more than two alcoholic beverages; current treatment for cancer, and estimated life expectancy less than 4 years. Inclusion/exclusion will be verified using the demographics and medical history.
Where this trial is running
Arlington, Texas
- University of Texas Arlington — Arlington, Texas, United States (RECRUITING)
Study contacts
- Study coordinator: Michael Nelson, PhD
- Email: michael.nelson3@uta.edu
- Phone: 8175130383
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aging, MRI, Cognitive Function, Exercise Science, Remote Monitoring