Understanding hospital-acquired respiratory virus infections
Hospital-acquired Respiratory Viral Infection: A Prospective Multicenter Study in France
This study is trying to learn more about respiratory virus infections that people catch in hospitals and see how vaccines might help prevent them.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 4 sites (Bordeaux and 3 other locations) |
| Trial ID | NCT06643039 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate hospital-acquired viral respiratory infections (HAVRI) in France, focusing on their epidemiology and the impact of vaccination on prevention. It will involve a multicenter approach across four hospitals, collecting data from hospitalized patients and healthcare professionals presenting with influenza-like illness. Participants will undergo nasopharyngeal swabs and complete questionnaires to gather clinical characteristics and potential sources of transmission. The goal is to enhance understanding of HAVRI and improve infection control measures.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who are hospitalized or healthcare professionals presenting with influenza-like symptoms.
Not a fit: Patients who are pregnant, breastfeeding, or under legal protection measures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies and reduced incidence of hospital-acquired respiratory infections.
How similar studies have performed: Other studies have shown success in understanding and controlling nosocomial infections, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults\> 18 years old * Hospitalized patient or health care professionals presenting an ILI on admission or during the stay, meeting the following definition: fever greater than 37.8° C in the absence of taking antipyretics and/or cough or pharyngeal pain. * Signed consent form Exclusion Criteria: * Pregnant, parturient or breastfeeding women * individuals deprived of their liberty by a judicial or administrative decision * Individuals subject to psychiatric care * Individuals admitted to a health or social establishment for purposes other than research * Individuals under a legal protection measure (guardianship, curatorship) * Individuals not affiliated to a social security insurance
Where this trial is running
Bordeaux and 3 other locations
- Pellegrin Hospital — Bordeaux, France (Not_yet_recruiting)
- CHU Dijon — Dijon, France (Not_yet_recruiting)
- Edouard Herriot Hospital — Lyon, France (Recruiting)
- Bichat Hospital — Paris, France (Not_yet_recruiting)
Study contacts
- Study coordinator: Philippe VANHEMS, MD, PhD
- Email: Philippe.vanhems@chu-lyon.fr
- Phone: +33 4 72 11 07 20
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.