Understanding Hepatitis D and its impact on patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The D-SOLVE cohorts aim to comprehensively analyze a large group of patients infected with Hepatitis D virus (HDV) to identify key demographic, clinical, and immunological factors that influence disease outcomes. This multicenter observational study will collect both retrospective and prospective data from 750 HDV patients across four European centers. The goal is to enhance personalized treatment strategies and improve patient management by understanding the individual host responses to HDV infection. Additionally, the study will focus on identifying biomarkers that could predict treatment responses and disease progression.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Anti-HDV positive
* ≥18 years old
* Sex: m/f/d
* Informed consent for prospective procedures

Exclusion Criteria:

* Anti-HDV negative

Where it's running

• Hannover Medical School, Department of Gastroenterology, Hepatology, Infectious Disease and Endocrinology
  Hanover, Germany Recruiting
• Institutul de Boli Infectioase "Prof. Dr. Matei Bals"
  Bucharest, Romania Recruiting
• Karolinska University Hospital and Karolinska Institutet
  Stockholm, Sweden Recruiting
• Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (University of Milan)
  Milan, Italy Not yet recruiting

Study contacts

• Principal investigator: Markus Cornberg — Hannover Medical School
• Study coordinator: Petra Dörge
• Email: doerge.petra@mh-hannover.de
• Phone: +495115326057

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.