Understanding Hepatitis B Virus Characteristics and Resistance

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with chronic hepatitis B (CHB) to analyze the molecular characteristics of the hepatitis B virus (HBV), including its integration, mutations, and drug resistance. Participants will be divided into two cohorts: one receiving antiviral treatment and monitored for HBV-related complications, and another assessed at a single time point without treatment. Blood and liver tissue samples will be collected to investigate HBV genotypes and their association with clinical outcomes. The goal is to enhance understanding of HBV's behavior and resistance patterns in different patient populations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with hepatitis B surface antigen positive.
* Patients who have complete demographic information, clinical data and retained blood samples or liver tissue samples

Exclusion Criteria:

* Subject who without blood samples or liver tissue samples

Where it's running

• Beijing Friendship Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Xiaoning Wu
• Email: byfriendship145@163.com
• Phone: 86+(010)6313-8665

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.