Understanding health outcomes in patients with COVID-19 and influenza

Patient-Reported Outcomes Associated With COVID-19 and Influenza: A Prospective Survey Study on Outpatient Symptomatic Adults With Test-Confirmed Illness in the United States

Observational Pfizer · NCT05160636

This study is trying to understand how COVID-19 and influenza affect people's health and symptoms by collecting information from adults about their experiences and vaccine history over six months.

Quick facts

Study typeObservational
Enrollment999 (estimated)
Ages18 Years and up
SexAll
SponsorPfizer Industry-sponsored
Locations1 site (Woonsocket, Rhode Island)
Trial IDNCT05160636 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the health-related outcomes and symptoms of individuals diagnosed with COVID-19 or influenza. Participants aged 18 and older will be enrolled based on confirmed test results and reported symptoms. Over a six-month period, the study will collect data through questionnaires regarding their health status and vaccine history. The study will analyze outcomes separately for COVID-19 and influenza cohorts, focusing on patient-reported outcomes and the impact of COVID-19 vaccines.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have tested positive for COVID-19 or influenza and reported at least one symptom.

Not a fit: Patients who have not reported any symptoms or do not have a confirmed diagnosis of COVID-19 or influenza will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the health impacts of COVID-19 and influenza, potentially guiding better patient care and treatment strategies.

How similar studies have performed: Other studies have successfully explored patient-reported outcomes in similar contexts, indicating a promising approach to understanding the health impacts of viral infections.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 or older
* Self-reported at least one symptom in the CVS Health pre-test screening questionnaire
* Positive result reported from diagnostic test for COVID-19 (or influenza in updated analysis)
* Evidence of a signed and dated informed consent through electronic consent process indicating that the participant has been informed of all pertinent aspects of the study
* Able to complete the questionnaires by themselves in English or Spanish

Exclusion Criteria:

- No symptoms reported in the study screening questionnaire

Where this trial is running

Woonsocket, Rhode Island

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COVID-19Coronavirus Disease 2019InfluenzaPatient-Reported OutcomesHumanistic BurdenQuality of LifeDisease Symptoms AssessmentSARS-CoV-2
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.