Understanding diet and nutrition in adults with Sickle Cell Disease
Official title: Observational Study of Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease
Run by National Institutes of Health Clinical Center (CC) · NCT05170412 · Data updated 2026-11-12
This study looks at how diet and nutrition affect the health of adults with Sickle Cell Disease to see what changes might help them feel better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 120 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Status | Recruiting |
| Started | May 26, 2022 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | September 18, 2026 |
| Trial ID | NCT05170412 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with a documented clinical diagnosis of Sickle Cell Disease.
✕Probably not a fit
Patients who are under 18 years of age or have Sickle Cell trait genotype may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess dietary intake and behaviors among adults with Sickle Cell Disease (SCD) to understand how these factors influence their overall health. Participants will undergo a review of their medical records, physical exams, and dietary assessments through surveys and laboratory results. The study will explore associations between dietary habits, clinical severity, psychosocial health, and social determinants of health. By utilizing a cross-sectional design, the research seeks to gather comprehensive data on the nutritional status of individuals with various clinical phenotypes of SCD.
Why it matters
Potential benefit: If successful, this study could provide insights into how dietary interventions may improve health outcomes for patients with Sickle Cell Disease.
How similar studies have gone: While there is ongoing research into the dietary impacts on Sickle Cell Disease, this specific approach focusing on dietary behaviors and social determinants is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, the participant must: 1. State their willingness to complete all study procedures for the duration of the study 2. 18 years of age or older at the time of screening 3. Have a documented clinical diagnosis (upon review of medical records) of SCD or presence of a SCD hemoglobinopathy genotype HbSS, HgSC, HbSB 0 or HBSB+ EXCLUSION CRITERIA: The following criteria will exclude any individual from participating in the study: 1. Less than 18 years of age 2. Unable to speak, read, write, and/or understand English 3. Presence of a condition or illness that will hamper the individual from giving informed consent (e.g. cognitive impairment) 4. SCD trait genotype 5. Currently undergoing inpatient treatment in any hospital for SCD at the time of screening 6. Pregnancy at the time of screening
Where it's running
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National Institutes of Health Clinical Center
Bethesda, Maryland, United States Recruiting
Study contacts
- Principal investigator: Nicole M Farmer, M.D. — National Institutes of Health Clinical Center (CC)
- Study coordinator: Stephanie L Wildridge, R.N.
- Email: wildridgesl@mail.nih.gov
- Phone: (240) 927-2603
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.