Understanding diet and nutrition in adults with Sickle Cell Disease
Observational Study of Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease
This study looks at how diet and nutrition affect the health of adults with Sickle Cell Disease to see what changes might help them feel better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 120 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT05170412 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess dietary intake and behaviors among adults with Sickle Cell Disease (SCD) to understand how these factors influence their overall health. Participants will undergo a review of their medical records, physical exams, and dietary assessments through surveys and laboratory results. The study will explore associations between dietary habits, clinical severity, psychosocial health, and social determinants of health. By utilizing a cross-sectional design, the research seeks to gather comprehensive data on the nutritional status of individuals with various clinical phenotypes of SCD.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with a documented clinical diagnosis of Sickle Cell Disease.
Not a fit: Patients who are under 18 years of age or have Sickle Cell trait genotype may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how dietary interventions may improve health outcomes for patients with Sickle Cell Disease.
How similar studies have performed: While there is ongoing research into the dietary impacts on Sickle Cell Disease, this specific approach focusing on dietary behaviors and social determinants is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, the participant must: 1. State their willingness to complete all study procedures for the duration of the study 2. 18 years of age or older at the time of screening 3. Have a documented clinical diagnosis (upon review of medical records) of SCD or presence of a SCD hemoglobinopathy genotype HbSS, HgSC, HbSB 0 or HBSB+ EXCLUSION CRITERIA: The following criteria will exclude any individual from participating in the study: 1. Less than 18 years of age 2. Unable to speak, read, write, and/or understand English 3. Presence of a condition or illness that will hamper the individual from giving informed consent (e.g. cognitive impairment) 4. SCD trait genotype 5. Currently undergoing inpatient treatment in any hospital for SCD at the time of screening 6. Pregnancy at the time of screening
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Nicole M Farmer, M.D. — National Institutes of Health Clinical Center (CC)
- Study coordinator: Stephanie L Wildridge, R.N.
- Email: wildridgesl@mail.nih.gov
- Phone: (240) 927-2603
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.