Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

Understanding colorectal cancer in Hispanic patients

Official title: Confronting Cancer as a Community

Run by University of Southern California · NCT06063928 · Data updated 2026-11-12

This study looks at Hispanic patients with colorectal cancer to see how their genes and gut health affect their treatment and outcomes.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorUniversity of Southern California
Academic / other
Locations2 sites (Los Angeles, California and 1 other locations)
StatusRecruiting
StartedMay 25, 2022
Main results expectedMay 25, 2027
Study endsMay 25, 2028
Registry record updatedJune 2, 2026
Trial IDNCT06063928 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Hispanic individuals aged 18 and older who have been diagnosed with colon or rectal cancer and have archived tumor tissue samples.

Probably not a fit

Patients who do not identify as Hispanic or those unable to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a detailed cohort of Hispanic patients diagnosed with colorectal cancer, collecting genetic, clinical, and outcome data. By analyzing blood and tumor tissue samples, the study seeks to identify genomic predictors of treatment outcomes and explore the gut microbiome's role in cancer progression. Additionally, it will assess patient engagement in genetic testing and the impact of comorbidities on treatment responses. The ultimate goal is to enhance personalized medicine approaches for this population.

Why it matters

Potential benefit: If successful, this study could lead to more effective, personalized treatment options for Hispanic patients with colorectal cancer.

How similar studies have gone: Other studies have shown promise in using genomic data to tailor cancer treatments, indicating that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-reported Hispanic ethnicity
* Diagnosed with colon or rectal cancer (at any time and stage; lifetime diagnosis and in survival are eligible)
* Has a tumor tissue sample archived or plans to have tissue archived from a standard care procedure
* Age \>= 18 years
* Ability to understand and the willingness to sign a written informed consent.
* For those who would like to participate in the optional microbiome characterization aspect of the study, the patient will have to be under 40 years old at any clinical cancer stage or over 60 years old at any clinical cancer stage.

Exclusion Criteria:

* Inability to understand and the willingness to sign a written informed consent

Where it's running

  • Los Angeles County-USC Medical Center
    Los Angeles, California, United States
    Recruiting
  • USC / Norris Comprehensive Cancer Center
    Los Angeles, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.