Understanding colorectal cancer in Hispanic patients
Confronting Cancer as a Community
This study looks at Hispanic patients with colorectal cancer to see how their genes and gut health affect their treatment and outcomes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Southern California Academic / other |
| Locations | 2 sites (Los Angeles, California and 1 other locations) |
| Trial ID | NCT06063928 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a detailed cohort of Hispanic patients diagnosed with colorectal cancer, collecting genetic, clinical, and outcome data. By analyzing blood and tumor tissue samples, the study seeks to identify genomic predictors of treatment outcomes and explore the gut microbiome's role in cancer progression. Additionally, it will assess patient engagement in genetic testing and the impact of comorbidities on treatment responses. The ultimate goal is to enhance personalized medicine approaches for this population.
Who should consider this trial
Good fit: Ideal candidates are Hispanic individuals aged 18 and older who have been diagnosed with colon or rectal cancer and have archived tumor tissue samples.
Not a fit: Patients who do not identify as Hispanic or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective, personalized treatment options for Hispanic patients with colorectal cancer.
How similar studies have performed: Other studies have shown promise in using genomic data to tailor cancer treatments, indicating that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Self-reported Hispanic ethnicity * Diagnosed with colon or rectal cancer (at any time and stage; lifetime diagnosis and in survival are eligible) * Has a tumor tissue sample archived or plans to have tissue archived from a standard care procedure * Age \>= 18 years * Ability to understand and the willingness to sign a written informed consent. * For those who would like to participate in the optional microbiome characterization aspect of the study, the patient will have to be under 40 years old at any clinical cancer stage or over 60 years old at any clinical cancer stage. Exclusion Criteria: * Inability to understand and the willingness to sign a written informed consent
Where this trial is running
Los Angeles, California and 1 other locations
- Los Angeles County-USC Medical Center — Los Angeles, California, United States (Recruiting)
- USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States (Recruiting)
Study contacts
- Principal investigator: Heinz-Josef Lenz, MD — University of Southern California
- Study coordinator: Ashley Noriega
- Email: Ashley.Noriega@med.usc.edu
- Phone: 323-865-3000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.