Understanding colorectal cancer in Hispanic patients
Official title: Confronting Cancer as a Community
Run by University of Southern California · NCT06063928 · Data updated 2026-11-12
This study looks at Hispanic patients with colorectal cancer to see how their genes and gut health affect their treatment and outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | University of Southern California Academic / other |
| Locations | 2 sites (Los Angeles, California and 1 other locations) |
| Status | Recruiting |
| Started | May 25, 2022 |
| Main results expected | May 25, 2027 |
| Study ends | May 25, 2028 |
| Registry record updated | June 2, 2026 |
| Trial ID | NCT06063928 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Hispanic individuals aged 18 and older who have been diagnosed with colon or rectal cancer and have archived tumor tissue samples.
✕Probably not a fit
Patients who do not identify as Hispanic or those unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a detailed cohort of Hispanic patients diagnosed with colorectal cancer, collecting genetic, clinical, and outcome data. By analyzing blood and tumor tissue samples, the study seeks to identify genomic predictors of treatment outcomes and explore the gut microbiome's role in cancer progression. Additionally, it will assess patient engagement in genetic testing and the impact of comorbidities on treatment responses. The ultimate goal is to enhance personalized medicine approaches for this population.
Why it matters
Potential benefit: If successful, this study could lead to more effective, personalized treatment options for Hispanic patients with colorectal cancer.
How similar studies have gone: Other studies have shown promise in using genomic data to tailor cancer treatments, indicating that this approach may yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Self-reported Hispanic ethnicity * Diagnosed with colon or rectal cancer (at any time and stage; lifetime diagnosis and in survival are eligible) * Has a tumor tissue sample archived or plans to have tissue archived from a standard care procedure * Age \>= 18 years * Ability to understand and the willingness to sign a written informed consent. * For those who would like to participate in the optional microbiome characterization aspect of the study, the patient will have to be under 40 years old at any clinical cancer stage or over 60 years old at any clinical cancer stage. Exclusion Criteria: * Inability to understand and the willingness to sign a written informed consent
Where it's running
-
Los Angeles County-USC Medical Center
Los Angeles, California, United States Recruiting -
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States Recruiting
Study contacts
- Principal investigator: Heinz-Josef Lenz, MD — University of Southern California
- Study coordinator: Ashley Noriega
- Email: Ashley.Noriega@med.usc.edu
- Phone: 323-865-3000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.